Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 11/20 | 0.64 |
| ▸ | THRB | P10828 | 11/20 | 0.64 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RARB | P10826 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RARA | P10276 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13959593 | 0.94 | ALDH1A1 (0.57) | THRATHRBHAO1ALDH1A1RARB | |
| SCHEMBL10583784 | 0.86 | THRA (0.65) | THRATHRBHAO1ALDH1A1RARB | |
| SCHEMBL12563620 | 0.85 | ALDH1A1 (0.67) | THRATHRBHAO1ALDH1A1RARB | |
| SCHEMBL11346510 | 0.84 | ESR1 (0.66) | THRATHRBHAO1ALDH1A1RARB | |
| SCHEMBL2349788 | 0.84 | ALDH1A1 (0.65) | THRATHRBHAO1ALDH1A1RARB | |
| SCHEMBL6282350 | 0.84 | THRA (0.61) | THRATHRBHAO1ALDH1A1RARB | |
| SCHEMBL17857869 | 0.83 | ESR1 (0.61) | THRATHRBALDH1A1 | |
| SCHEMBL29087838 | 0.83 | ALDH1A1 (0.67) | THRATHRBHAO1ALDH1A1RARB | |
| SCHEMBL4191545 | 0.82 | ESR1 (0.63) | ALDH1A1 | |
| SCHEMBL340275 | 0.82 | ESR1 (0.63) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7479575-B2 | Method for preparing para-phenyl alkynyl benzaldehydes | LABORATOIRES SERONO SA (CH) | 2009-01-20 | — | — | US | disclosed |
| US-7479575-B2 | Method for preparing para-phenyl alkynyl benzaldehydes | LABORATOIRES SERONO SA (CH) | 2009-01-20 | — | — | US | disclosed |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2008-05-08 | — | — | US | disclosed |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2008-05-08 | — | — | US | disclosed |
| EP-1675813-B1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | SERONO LAB (CH) | 2007-12-19 | — | — | EP | disclosed |
| EP-1675813-A1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | Applied Research Systems ARS Holding N.V. (NL) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037758-A1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | TNNC1, CPT1B, MUSK | THRA 3478/4885THRB 2718/4885HAO1 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.