Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12326172 | 0.91 | PTGS2 (0.53) | AHRPTGS2PTGS1KMOMEN1 | |
| SCHEMBL403698 | 0.82 | ADORA2A (0.55) | PTGS2PTGS1KMOMEN1KMT2A | |
| SCHEMBL13906293 | 0.82 | ACHE (0.54) | PTGS2PTGS1KMOMEN1POLB | |
| SCHEMBL29375895 | 0.82 | ADORA2A (0.55) | PTGS2PTGS1KMOMEN1KMT2A | |
| SCHEMBL12603887 | 0.82 | TAS1R3 (0.49) | PTGS2PTGS1KMOALDH1A1HSD17B10 | |
| SCHEMBL23909988 | 0.80 | ALDH1A1 (0.48) | PTGS2PTGS1KMOMEN1POLB | |
| SCHEMBL13906296 | 0.80 | PTGS2 (0.50) | PTGS2PTGS1KMOKMT2APDGFRB | |
| SCHEMBL16841763 | 0.79 | MEN1 (0.52) | PTGS2PTGS1KMOERN1MEN1 | |
| SCHEMBL6368263 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1KMOMEN1KMT2A | |
| SCHEMBL12603809 | 0.77 | KMT2A (0.47) | PTGS2PTGS1KMOERN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090269857-A1 | Instruments for detecting low-molecular weight substance | FUJIKURA KASEI CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20050148097-A1 | Instruments for detecting low-molecular weight substance | ENBIOTEC LABORATORIES C., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1489420-A1 | INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE | Enbiotec Laboratories Co., Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |