Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 15/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4443004 | 0.99 | NSD2 (0.71) | NSD2CA1CA2CYP19A1LMNA | |
| SCHEMBL4445436 | 0.88 | NSD2 (0.67) | NSD2CYP19A1 | |
| Hydrochloric Acid SCHEMBL4448157 | 0.87 | NSD2 (0.67) | NSD2CYP19A1 | |
| SCHEMBL4483894 | 0.85 | CA2 (0.55) | NSD2CA1CA2CYP19A1LMNA | |
| SCHEMBL4450802 | 0.84 | NSD2 (0.82) | NSD2CA1CA2 | |
| SCHEMBL4450751 | 0.83 | NSD2 (0.76) | NSD2CA1CA2 | |
| SCHEMBL4445013 | 0.83 | NSD2 (1.00) | NSD2CA1CA2LMNA | |
| Hydrochloric Acid SCHEMBL4445018 | 0.83 | NSD2 (0.82) | NSD2CA1CA2 | |
| SCHEMBL4441197 | 0.83 | NSD2 (1.00) | NSD2 | |
| Hydrochloric Acid SCHEMBL4454755 | 0.82 | NSD2 (0.76) | NSD2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |