Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206058 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ATAAR1LMNA | |
| SCHEMBL4454869 | 0.82 | CTSK (0.45) | ALDH1A1MEN1KMT2ATAAR1SMN1; SMN2 | |
| SCHEMBL27792966 | 0.82 | CTSK (0.45) | ALDH1A1MEN1KMT2ATAAR1SMN1; SMN2 | |
| SCHEMBL3782505 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL8876050 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL9293035 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL8314307 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL2786517 | 0.79 | LMNA (0.54) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL13621588 | 0.78 | LMNA (0.59) | ALDH1A1KMT2ALMNAHPGDHDAC1 | |
| SCHEMBL13048136 | 0.78 | LMNA (0.59) | ALDH1A1KMT2ALMNAHPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643626-A4 | CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL. | RES CORP TECHNOLOGIES INC (US) | 1995-12-06 | — | — | EP | claimed |
| EP-0643626-A1 | CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-22 | — | — | EP | claimed |