SCHEMBL4454982

SCHEMBL4454982

CC(C)(CCCCc1ccccc1)O[SiH3]

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
MAOA P21397 1/20 0.45
SIGMAR1 Q99720 8/20 0.44
MAOB P27338 2/20 0.44
NAAA Q02083 1/20 0.43
IDO1 P14902 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28731688 0.98 SIGMAR1 (0.47) L3MBTL1MAOASIGMAR1MAOB
SCHEMBL2869652 0.96 IDO1 (0.42) L3MBTL1MAOASIGMAR1NAAAIDO1
SCHEMBL964291 0.88 ALDH1A1 (0.39) IDO1
SCHEMBL15733562 0.81 TAAR1 (0.40) L3MBTL1SIGMAR1MAOB
SCHEMBL15733704 0.80 TAAR1 (0.39) L3MBTL1SIGMAR1
SCHEMBL15735717 0.80 TAAR1 (0.39) L3MBTL1SIGMAR1
SCHEMBL15734434 0.80 TAAR1 (0.46) MAOBIDO1
SCHEMBL4742953 0.79 MAOA (0.52) L3MBTL1MAOASIGMAR1MAOB
SCHEMBL16714737 0.79 MAOA (0.56) MAOASIGMAR1
SCHEMBL16714770 0.79 MAOA (0.61) MAOASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
US-8808446-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2014-08-19 US disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed