SCHEMBL4455147

SCHEMBL4455147

CO[Si](C)(OC)c1ccc(N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 7/20 0.44
MAPK1 P28482 2/20 0.44
ALDH1A1 P00352 6/20 0.42
CYP3A4 P08684 4/20 0.42
MAPT P10636 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TP53 P04637 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ACHE P22303 2/20 0.38
TSHR P16473 2/20 0.36
APP P05067 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397346 0.87 CA12 (0.30)
SCHEMBL16454969 0.83 TDP1 (0.35) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL27755631 0.82 TDP1 (0.34) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL1172627 0.80 TDP1 (0.44) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL5421236 0.79
SCHEMBL5421307 0.79
SCHEMBL6436993 0.79 ESR2 (0.32) KDM4E
SCHEMBL110157 0.77 TDP1 (0.46) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL5421459 0.77
SCHEMBL1173115 0.77 ALDH1A1 (0.50) TDP1MAPK1ALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210017420-A1 STRUCTURE BODY, SENSOR, AND METHOD FOR PRODUCING STRUCTURE BODY DENSO CORPORATION (JP) 2021-01-21 US claimed
WO-2019193943-A1 STRUCTURE BODY, SENSOR, AND STRUCTURE BODY PRODUCTION METHOD 株式会社デンソー 2019-10-10 WO claimed
EP-3340253-A1 UV-RESISTANT ELECTRODE ASSEMBLY Solvay SA (BE) 2018-06-27 EP claimed
EP-3340252-A1 ELECTRODE ASSEMBLY Solvay SA (BE) 2018-06-27 EP claimed
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
US-20230302533-A1 Additive Manufacturing Powder And Additively Manufactured Body SEIKO EPSON CORPORATION (JP) 2023-09-28 US disclosed
CN-110857371-B Cured film and color filter 捷恩智株式会社 2023-05-30 CN disclosed
US-11485877-B2 Structure body, sensor, and method for producing structure body DENSO CORPORATION (JP) 2022-11-01 US disclosed
US-20210017420-A1 STRUCTURE BODY, SENSOR, AND METHOD FOR PRODUCING STRUCTURE BODY DENSO CORPORATION (JP) 2021-01-21 US disclosed
US-20210017420-A1 STRUCTURE BODY, SENSOR, AND METHOD FOR PRODUCING STRUCTURE BODY DENSO CORPORATION (JP) 2021-01-21 US disclosed
WO-2019193943-A1 STRUCTURE BODY, SENSOR, AND STRUCTURE BODY PRODUCTION METHOD 株式会社デンソー 2019-10-10 WO disclosed
WO-2019193943-A1 STRUCTURE BODY, SENSOR, AND STRUCTURE BODY PRODUCTION METHOD 株式会社デンソー 2019-10-10 WO disclosed
EP-0337698-A2 Photosensitive Polymer Chisso Corporation (JP) 1989-10-18 EP disclosed
EP-0330456-A1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORPORATION (JP) 1989-08-30 EP disclosed
US-4783151-A Devices utilizing pendant quinodimethane-containing polymers Hochst Celanese Corporation (US) 1988-11-08 US disclosed
EP-0280499-A2 Novel aminohydrocarbyl-substituted ketoximosilanes DOW CORNING CORPORATION (US) 1988-08-31 EP disclosed
US-4719281-A Pendant quinodimethane-containing polymer HOECHST CELANESE CORPORATION (US) 1988-01-12 US disclosed
US-4705877-A Novel aminohydrocarbyl-substituted ketoximosilanes DOW CORNING CORPORATION (US) 1987-11-10 US disclosed
EP-0243806-A2 Pendant quinodimethane-containing polymers CELANESE CORPORATION (US) 1987-11-04 EP disclosed
EP-0190487-A2 Soluble polyimide-siloxane precursor and process for producing it Chisso Corporation (JP) 1986-08-13 EP disclosed