SCHEMBL110157

SCHEMBL110157

CO[Si](OC)(OC)c1ccc(N)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 7/20 0.46
MAPK1 P28482 3/20 0.46
ALDH1A1 P00352 8/20 0.44
CYP3A4 P08684 4/20 0.44
MAPT P10636 3/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ACHE P22303 1/20 0.39
TSHR P16473 2/20 0.38
APP P05067 2/20 0.37
NR4A1 P22736 1/20 0.37
TP53 P04637 3/20 0.36
TEAD4 Q15561 1/20 0.36
CYP19A1 P11511 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
NFKB1 P19838 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2605581 0.90 TDP1 (0.42) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL50828 0.86 KDM4E (0.32) MAPK1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL16454969 0.81 TDP1 (0.35) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL15966685 0.80 TDP1 (0.35) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL1173115 0.79 ALDH1A1 (0.50) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL3353844 0.78 ESR2 (0.33) MAPK1TP53SMN1; SMN2NPC1RAB9A
SCHEMBL5404962 0.78
SCHEMBL1172627 0.77 TDP1 (0.44) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL4455147 0.77 TDP1 (0.44) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL2605577 0.77 ALDH1A1 (0.40) TDP1MAPK1ALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3342 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121155358-B Ultrafiltration membrane, preparation method thereof and application of ultrafiltration membrane in pure water treatment 深圳市纯水一号科技股份有限公司 2026-05-19 CN claimed
US-20260028481-A1 WATERBORNE SILICONE EMULSION, METHOD FOR MAKING SAME, AND COMPOSITIONS COMPRISING SUCH EMULSIONS MOMENTIVE PERFORMANCE MAT INC (US) 2026-01-29 US claimed
EP-4684006-A1 ASSAYS FOR CHARACTERIZATION OF EXTRACELLULAR VESICLES AND METHODS OF USING THE SAME The Translational Genomics Research Institute (US) 2026-01-28 EP claimed
WO-2025224574-A1 COATED NONWOVEN POROUS ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-10-30 WO claimed
EP-4578035-A1 WET ELECTROLYTIC CAPACITOR CONTAINING A GELLED WORKING ELECTROLYTE KYOCERA AVX Components Corporation (US) 2025-07-02 EP claimed
CN-120189762-A Carbon fiber-based polymer filter material and preparation method thereof 山西智禹水利环保科技有限公司 2025-06-24 CN claimed
CN-120158137-A Preparation method of modified fumed silica for improving glossiness of ink 山东弘睿通新材料科技有限公司 2025-06-17 CN claimed
CN-120137354-A Chlorine salt freezing and thawing resistant glass fiber reinforced plastic composite material, preparation method and application thereof in preparation of water intake head 中交第一航务工程勘察设计院有限公司 2025-06-13 CN claimed
CN-120148988-A Low-cost preparation process of high-strength mica column 浙江荣泰电工器材股份有限公司 2025-06-13 CN claimed
CN-120041122-A Epoxy resin underfill adhesive and preparation method thereof 深圳先进电子材料国际创新研究院 2025-05-27 CN claimed
EP-0381742-A1 RECEPTOR MEDIATED ENDOCYTOSIS TYPE MRI CONTRAST AGENTS. ADVANCED MAGNETICS INC (US) 1990-08-16 EP claimed
WO-1990001295-A1 RECEPTOR MEDIATED ENDOCYTOSIS TYPE MRI CONTRAST AGENTS ADVANCED MAGNETICS, INCORPORATED (US) 1990-02-22 WO claimed
US-4695392-A Magnetic particles for use in separations ADVANCED MAGNETICS INC. (US) 1987-09-22 US claimed
US-4695393-A POLYMERIZING A SILANE ADVANCED MAGNETICS INC. (US) 1987-09-22 US claimed
US-4680326-A Poly(arylene sulfide) composition with improved insulation resistance and cracking resistance PHILLIPS PETROLEUM COMPANY (US) 1987-07-14 US claimed
EP-0199278-A2 Poly(Arylene Sulfide) compositions with improved insulation resistance and cracking resistance PHILLIPS PETROLEUM COMPANY (US) 1986-10-29 EP claimed
US-4554088-A BIOAFFINITY ADSORBENT DOUPLED TO POLYSILOXANE COATING ADVANCED MAGNETICS INC. (US) 1985-11-19 US claimed
EP-0125995-A2 Magnetic particles for use in separations ADVANCED MAGNETICS, INC. (US) 1984-11-21 EP claimed
US-4451601-A REDUCING MELT FLOW RATE PHILLIPS PETROLEUM COMPANY (US) 1984-05-29 US claimed
EP-0074632-A2 Glass-filled polyarylene sulfide compositions containing organosilanes PHILLIPS PETROLEUM COMPANY (US) 1983-03-23 EP claimed