Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023605 | 0.91 | TDP1 (0.43) | ALDH1A1TDP1CYP3A4MAPK1MAPT | |
| SCHEMBL110157 | 0.79 | TDP1 (0.46) | ALDH1A1TDP1CYP3A4MAPK1MAPT | |
| SCHEMBL1172627 | 0.77 | TDP1 (0.44) | ALDH1A1TDP1CYP3A4MAPK1MAPT | |
| SCHEMBL4455147 | 0.77 | TDP1 (0.44) | ALDH1A1TDP1CYP3A4MAPK1MAPT | |
| SCHEMBL23521412 | 0.76 | — | — | |
| SCHEMBL706592 | 0.76 | ESR1 (0.41) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL297138 | 0.76 | ACHE (0.44) | ALDH1A1TDP1CYP3A4MAPTMEN1 | |
| SCHEMBL2605581 | 0.75 | TDP1 (0.42) | ALDH1A1TDP1CYP3A4MAPK1MAPT | |
| SCHEMBL28422604 | 0.75 | TDP1 (0.42) | ALDH1A1TDP1CYP3A4MAPK1MAPT | |
| SCHEMBL30423939 | 0.75 | IDO1 (0.42) | ALDH1A1TDP1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210017420-A1 | STRUCTURE BODY, SENSOR, AND METHOD FOR PRODUCING STRUCTURE BODY | DENSO CORPORATION (JP) | 2021-01-21 | — | — | US | disclosed |
| WO-2019193943-A1 | STRUCTURE BODY, SENSOR, AND STRUCTURE BODY PRODUCTION METHOD | 株式会社デンソー | 2019-10-10 | — | — | WO | disclosed |
| US-7932412-B2 | Method of manufacturing an aminoaryl-containing organosilicon compound and method of manufacturing an intermediate product of the aforementioned compound | DOW CORNING TORAY CO., LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20110040114-A1 | METHOD OF MANUFACTURING AN AMINOARYL-CONTAINING ORGANOSILICON COMPOUND AND METHOD OF MANUFACTURING AN INTERMEDIATE PRODUCT OF THE AFOREMENTIONED COMPOUND | DOW TORAY CO., LTD. (JP) | 2011-02-17 | — | — | US | disclosed |
| EP-1797103-B1 | Preparation of an aminoaryl-containing organosilicon compound and intermediate used in its preparation | DOW CORNING TORAY CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7847116-B2 | Method of manufacturing an aminoaryl-containing organosilicon compound and method of manufacturing an intermediate product of the aforementioned compound | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20080242881-A1 | Method Of Manufacturing An Aminoaryl-Containing Organosilicon Compound And Method Of Manufacturing An Intermediate Product Of The Aforementioned Compound | DOW CORNING TORAY COMPANY, LTD. (JP) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040114-A1 | METHOD OF MANUFACTURING AN AMINOARYL-CONTAINING ORGANOSILICON COMPOUND AND METHOD OF MANUFACTURING AN INTERMEDIATE PRODUCT OF THE AFOREMENTIONED COMPOUND | DDC, AADAC, AADAT | ALDH1A1 2814/4885TDP1 4208/4885CYP3A4 256/4885 |
| US-20080242881-A1 | Method Of Manufacturing An Aminoaryl-Containing Organosilicon Compound And Method Of Manufacturing An Intermediate Product Of The Aforementioned Compound | DDC, AADAC, AADAT | ALDH1A1 2759/4885TDP1 4131/4885CYP3A4 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.