Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460123 | 0.87 | PPARA (0.56) | PPARGPPARAMEN1KMT2AMAPT | |
| SCHEMBL3272549 | 0.84 | PPARG (0.59) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3272547 | 0.84 | PPARG (0.59) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3801397 | 0.82 | LDHA (0.53) | PPARGPPARANPC1RAB9AMEN1 | |
| SCHEMBL28136422 | 0.82 | LDHA (0.53) | PPARGPPARANPC1RAB9AMEN1 | |
| SCHEMBL3739737 | 0.81 | LDHA (0.51) | PPARGPPARANPC1RAB9AMEN1 | |
| SCHEMBL7676911 | 0.81 | LDHA (0.51) | PPARGPPARANPC1RAB9AMEN1 | |
| SCHEMBL28246723 | 0.81 | LDHA (0.51) | PPARGPPARANPC1RAB9AMEN1 | |
| SCHEMBL4413232 | 0.81 | LDHA (0.51) | PPARGPPARANPC1RAB9AMEN1 | |
| SCHEMBL5208103 | 0.80 | LDHA (0.55) | NPC1RAB9ALDHAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |