Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTPRB | P23467 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373188 | 0.93 | LMNA (0.51) | LDHAALDH1A1LMNAPTPRBNPC1 | |
| SCHEMBL27649389 | 0.88 | ALDH1A1 (0.55) | LDHAALDH1A1LMNAPTPRBHTT | |
| SCHEMBL8039407 | 0.87 | ALDH1A1 (0.50) | LDHAALDH1A1LMNAPTPRBHTT | |
| SCHEMBL28136422 | 0.83 | LDHA (0.53) | LDHAHTTPOLBNPC1RAB9A | |
| SCHEMBL3801397 | 0.83 | LDHA (0.53) | LDHAHTTPOLBNPC1RAB9A | |
| SCHEMBL15708030 | 0.83 | LDHA (0.53) | LDHAHTTPOLBNPC1RAB9A | |
| SCHEMBL16892957 | 0.83 | PTPRB (0.51) | LDHAALDH1A1PTPRBHTTSMN1; SMN2 | |
| SCHEMBL3266754 | 0.83 | PTPRB (0.71) | LDHAPTPRBHTTSMN1; SMN2F2RL1 | |
| SCHEMBL7676911 | 0.81 | LDHA (0.51) | LDHAHTTPOLBNPC1RAB9A | |
| SCHEMBL4413232 | 0.81 | LDHA (0.51) | LDHAALDH1A1HTTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603930-B1 | PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS | KTB TUMORFORSCHUNGS GMBH (DE) | 2007-08-29 | — | — | EP | claimed |
| US-7141691-B2 | Protein-bound derivatives of platinum complexes containing cyclobutane1, 1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-11-28 | — | — | US | claimed |
| US-20060089341-A1 | Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-04-27 | — | — | US | claimed |
| US-8921514-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20110207699-A1 | Anti-Viral Compounds | Abbott Labaoratories (US) | 2011-08-25 | — | — | US | disclosed |
| EP-1603930-B1 | PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS | KTB TUMORFORSCHUNGS GMBH (DE) | 2007-08-29 | — | — | EP | disclosed |
| US-7141691-B2 | Protein-bound derivatives of platinum complexes containing cyclobutane1, 1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| US-20060089341-A1 | Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-04-27 | — | — | US | disclosed |
| EP-1603930-A1 | PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS | KTB Tumorforschungs GmbH (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004083223-A1 | PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS | KTB TUMORFORSCHUNGS GMBH (DE) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089341-A1 | Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands | DDB1, DCLRE1A, PDCD1LG2 | LDHA 1532/4885ALDH1A1 2885/4885LMNA 4654/4885 |
| US-20110207699-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | LDHA 2383/4885ALDH1A1 2858/4885LMNA 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.