SCHEMBL4455340

SCHEMBL4455340

CCOP(=O)(OCC)c1ccccc1CC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
POLB P06746 2/20 0.49
NPSR1 Q6W5P4 2/20 0.44
KCNH2 Q12809 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
ALDH1A1 P00352 3/20 0.41
ACHE P22303 1/20 0.41
NR1I2 O75469 1/20 0.40
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 2/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18486629 0.87 MEN1 (0.61) MEN1KMT2APOLBNPSR1KCNH2
SCHEMBL4458096 0.87 MEN1 (0.50) MEN1KMT2APOLBNPSR1KCNH2
SCHEMBL9177686 0.87 MEN1 (0.50) MEN1KMT2APOLBNPSR1KCNH2
SCHEMBL4462717 0.85 MEN1 (0.50) MEN1KMT2APOLBNPSR1ALDH1A1
SCHEMBL4452195 0.84 MEN1 (0.48) MEN1KMT2APOLBNPSR1KCNH2
SCHEMBL4451733 0.83 MEN1 (0.50) MEN1KMT2APOLBNPSR1KCNH2
SCHEMBL4451785 0.82 CYP3A4 (0.44) MEN1KMT2A
SCHEMBL4454668 0.82 L3MBTL1 (0.37) MEN1KMT2APOLBNPSR1CA12
SCHEMBL8374437 0.81 LIPG (0.46) MEN1KMT2A
SCHEMBL12229785 0.81 ALDH1A1 (0.58) MEN1KMT2APOLBNPSR1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293805-B Olefin polymerization solid catalytic component, component preparation method and catalyst system thereof 中国石油天然气股份有限公司 2021-03-09 CN claimed
CN-109293805-B Olefin polymerization solid catalytic component, component preparation method and catalyst system thereof 中国石油天然气股份有限公司 2021-03-09 CN disclosed
US-10550241-B2 Polytrimethylene terephthalate composition, polyester fiber, and methods for producing the same TEIJIN FRONTIER CO., LTD. (JP) 2020-02-04 US disclosed
EP-3249012-B1 POLYTRIMETHYLENE TEREPHTHALATE COMPOSITION, POLYESTER FIBERS, AND METHOD FOR PRODUCING SAME TEIJIN FRONTIER CO LTD (JP) 2019-08-21 EP disclosed
US-20180265667-A1 POLYTRIMETHYLENE TEREPHTHALATE COMPOSITION, POLYESTER FIBER, AND METHODS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2018-09-20 US disclosed
US-10017629-B2 Polyethylene-2,6-naphthalate composition with excellent blow moldability, and molded product thereof TEIJIN LIMITED (JP) 2018-07-10 US disclosed
EP-3109271-B1 POLYETHYLENE-2,6-NAPHTHALATE COMPOSITION WITH EXCELLENT BLOW MOLDABILITY, AND MOLDED PRODUCT THEREOF TEIJIN LTD (JP) 2018-03-28 EP disclosed
EP-3249012-A1 POLYTRIMETHYLENE TEREPHTHALATE COMPOSITION, POLYESTER FIBERS, AND METHOD FOR PRODUCING SAME Teijin Limited (JP) 2017-11-29 EP disclosed
EP-3109271-A1 POLYETHYLENE-2,6-NAPHTHALATE COMPOSITION WITH EXCELLENT BLOW MOLDABILITY, AND MOLDED PRODUCT THEREOF Teijin Limited (JP) 2016-12-28 EP disclosed
US-20160347934-A1 POLYETHYLENE-2,6-NAPHTHALATE COMPOSITION WITH EXCELLENT BLOW MOLDABILITY, AND MOLDED PRODUCT THEREOF TEIJIN LIMITED (JP) 2016-12-01 US disclosed
EP-2256124-A1 Phospho-indoles as HIV inhibitors IDENIX Pharmaceuticals, Inc. (US) 2010-12-01 EP disclosed
EP-1961757-B1 Phosphoindoles as HIV inhibitors IDENIX PHARMACEUTICALS INC (US) 2010-09-01 EP disclosed
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20090163444-A1 PHOSPHO-INDOLES AS HIV INHIBITORS IDENIX PHARMACEUTICALS LLC 2009-06-25 US disclosed
US-20090163444-A1 PHOSPHO-INDOLES AS HIV INHIBITORS IDENIX PHARMACEUTICALS LLC 2009-06-25 US disclosed
US-7534809-B2 Phospho-indoles as HIV inhibitors IDENIX PHARMACEUTICALS, INC. (US) 2009-05-19 US disclosed
US-7534809-B2 Phospho-indoles as HIV inhibitors IDENIX PHARMACEUTICALS, INC. (US) 2009-05-19 US disclosed
EP-1799696-B1 PHOSPHOINDOLES AS HIV INHIBITORS IDENIX PHARMACEUTICALS INC (US) 2008-11-12 EP disclosed
EP-1961757-A1 Phosphoindoles as HIV inhibitors IDENIX Pharmaceuticals, Inc. (US) 2008-08-27 EP disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163444-A1 PHOSPHO-INDOLES AS HIV INHIBITORS IDO1, PPP5C, INMT MEN1 3483/4885KMT2A 1767/4885POLB 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.