Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456595 | 0.91 | DGKA (0.40) | DGKADNM1ADRA2AADRA1ATSHR | |
| SCHEMBL5159381 | 0.89 | DGKA (0.48) | DGKADNM1ADRA2AADRA1ATSHR | |
| SCHEMBL5164186 | 0.87 | ADRA2A (0.43) | DGKADNM1ADRA2AADRA1ATSHR | |
| SCHEMBL4358005 | 0.84 | DGKA (0.53) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL31302270 | 0.84 | TSHR (0.41) | DGKATSHRNAAAMEN1KMT2A | |
| SCHEMBL13978973 | 0.83 | DGKA (0.50) | DGKADNM1ADRA2AADRA1ATSHR | |
| SCHEMBL4459130 | 0.83 | DGKA (0.41) | DGKADNM1ADRA2AADRA1APRSS1 | |
| SCHEMBL6271674 | 0.82 | DGKA (0.46) | DGKADNM1ADRA2AADRA1APRSS1 | |
| SCHEMBL8839460 | 0.81 | DGKA (0.65) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL8839367 | 0.81 | DGKA (0.65) | DGKADNM1TSHRPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | claimed |
| EP-1680469-A4 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2007-09-05 | — | — | EP | claimed |
| JP-2007509209-A | — | — | 2007-04-12 | — | — | JP | claimed |
| US-20060293423-A1 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2006-12-28 | — | — | US | claimed |
| EP-1680469-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | Lanxess Inc. (CA) | 2006-07-19 | — | — | EP | claimed |
| WO-2005040272-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC. (CA) | 2005-05-06 | — | — | WO | claimed |
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | disclosed |
| US-20080242771-A1 | Butyl Rubber Composition for Tire Treads | LANXESS INC. (CA) | 2008-10-02 | — | — | US | disclosed |
| EP-1680469-A4 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2007-09-05 | — | — | EP | disclosed |
| US-20060293423-A1 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2006-12-28 | — | — | US | disclosed |
| EP-1694764-A1 | BUTYL RUBBER COMPOSITION FOR TIRE TREADS | Lanxess Inc. (CA) | 2006-08-30 | — | — | EP | disclosed |
| EP-1680469-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | Lanxess Inc. (CA) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005056664-A1 | BUTYL RUBBER COMPOSITION FOR TIRE TREADS | LANXESS INC. (CA) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005040272-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC. (CA) | 2005-05-06 | — | — | WO | disclosed |