Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164186 | 0.94 | ADRA2A (0.43) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8839460 | 0.91 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8839286 | 0.91 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8839367 | 0.91 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL4358005 | 0.91 | DGKA (0.53) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL13978973 | 0.90 | DGKA (0.50) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL4455816 | 0.89 | DGKA (0.39) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL6271674 | 0.89 | DGKA (0.46) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL10277563 | 0.87 | TSHR (0.38) | DGKATSHRADRA2AADRA1AMAPT | |
| SCHEMBL20480726 | 0.87 | DGKA (0.36) | DGKADNM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207188-B1 | Curable silicone adhesive compositions | GEN ELECTRIC (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-0880053-B1 | Shading spacers for liquid crystal displays, process of producing such spacers, and liquid crystal display element comprising such spacers | NATOCO CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-6447922-B1 | BIS(TRIALKOXYSILYLALKYL)SUCCINATE ADHESION PROMOTER, A VINYL-CONTAINING POLYDIORGANOSILOXANE, A HYDROGEN-CONTAINING POLYSILOXANE, HYDROSILYLATION CATALYST; ROOM TEMPERATURE VULCANIZABLE | GENERAL ELECTRIC COMPANY | 2002-09-10 | — | — | US | disclosed |
| EP-1207188-A2 | Curable silicone adhesive compositions | GENERAL ELECTRIC COMPANY (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6268456-B1 | FILMS WITH REACTIVE SILYL GROUPS | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-07-31 | — | — | US | disclosed |
| US-6117500-A | CROSSLINKED POLYMER WITH DYE FIXED IN POLYMER WITH SILYL GROUP THAT CAN BE HYDROLYZED AND FORMING A SILOXANE BOND | NATOCO CO., LTD. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0830434-B1 | COATING COMPOSITION CONTAINING SILANE FUNCTIONALITY | DU PONT (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0880053-A2 | Shading spacers for liquid crystal displays, process of producing such spacers, and liquid crystal display element comprising such spacers | Natoco Paint Co., Ltd. (JP) | 1998-11-25 | — | — | EP | disclosed |
| EP-0830434-A1 | COATING COMPOSITION CONTAINING SILANE FUNCTIONALITY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996039468-A1 | COATING COMPOSITION CONTAINING SILANE FUNCTIONALITY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-12 | — | — | WO | disclosed |