Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456090 | 1.00 | NPC1 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4455228 | 0.77 | KMT2A (0.48) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4455232 | 0.77 | KMT2A (0.48) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3790984 | 0.72 | NPC1 (0.66) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2608442 | 0.72 | CCR4 (0.53) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20788543 | 0.71 | NPC1 (0.77) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4558249 | 0.70 | FDPS (0.49) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4763218 | 0.70 | ATAD2 (0.47) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11222516 | 0.70 | NPC1 (0.62) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2608447 | 0.69 | ATAD2 (0.63) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |