Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 6/20 | 0.46 |
| ▸ | CCR4 | P51679 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455228 | 1.00 | KMT2A (0.48) | KMT2AMEN1NPC1RAB9AMAPK1 | |
| SCHEMBL4466264 | 0.77 | KIF11 (0.45) | NPC1RAB9AMAPK1ALDH1A1KIF11 | |
| SCHEMBL4466274 | 0.77 | KIF11 (0.45) | NPC1RAB9AMAPK1ALDH1A1KIF11 | |
| SCHEMBL4456093 | 0.77 | NPC1 (0.48) | KMT2AMEN1NPC1RAB9AMAPK1 | |
| SCHEMBL4456090 | 0.77 | NPC1 (0.48) | KMT2AMEN1NPC1RAB9AMAPK1 | |
| SCHEMBL4468277 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1NPC1RAB9AMAPK1 | |
| SCHEMBL4458679 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1NPC1RAB9AMAPK1 | |
| SCHEMBL4458423 | 0.73 | ELOVL1 (0.46) | KMT2AMEN1MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4458415 | 0.73 | ELOVL1 (0.46) | KMT2AMEN1MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5967574 | 0.73 | KIF11 (0.54) | KIF11DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |