Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455141 | 0.80 | HDAC3 (0.56) | GAARAB9ANPC1MAPTKMT2A | |
| SCHEMBL4455136 | 0.80 | HDAC3 (0.56) | GAARAB9ANPC1MAPTKMT2A | |
| SCHEMBL4455148 | 0.74 | FDPS (0.46) | FDPSRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL4455160 | 0.74 | FDPS (0.46) | FDPSRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL4459618 | 0.72 | ALOX5 (0.54) | RAB9ANPC1MAPTPOLBKMT2A | |
| SCHEMBL4459625 | 0.72 | ALOX5 (0.54) | RAB9ANPC1MAPTPOLBKMT2A | |
| SCHEMBL4456093 | 0.70 | NPC1 (0.48) | GAARAB9ANPC1MAPTPOLB | |
| SCHEMBL4456090 | 0.70 | NPC1 (0.48) | GAARAB9ANPC1MAPTPOLB | |
| SCHEMBL13606506 | 0.70 | RAB9A (0.53) | GAARAB9ANPC1MAPTKMT2A | |
| SCHEMBL14706944 | 0.69 | SMN1; SMN2 (0.61) | RAB9ANPC1MAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |