Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.62 |
| ▸ | METAP2 | P50579 | 8/20 | 0.60 |
| ▸ | IDO1 | P14902 | 9/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22363550 | 0.78 | XDH (1.00) | XDH | |
| SCHEMBL21904932 | 0.75 | CYP1A2 (0.57) | KMT2A | |
| SCHEMBL28741907 | 0.75 | METAP2 (0.63) | XDHMETAP2IDO1KEAP1SIRT3 | |
| SCHEMBL29626795 | 0.75 | METAP2 (0.63) | XDHMETAP2IDO1KEAP1SIRT3 | |
| SCHEMBL13994029 | 0.75 | METAP2 (0.58) | XDHMETAP2IDO1KEAP1SIRT3 | |
| SCHEMBL28741748 | 0.75 | IDO1 (0.58) | XDHMETAP2IDO1KEAP1SIRT3 | |
| SCHEMBL21904995 | 0.74 | BTK (0.47) | KMT2A | |
| SCHEMBL30331540 | 0.73 | MGLL (0.78) | — | |
| SCHEMBL7511547 | 0.73 | MGLL (0.78) | — | |
| SCHEMBL25440056 | 0.73 | MGLL (0.56) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |