SCHEMBL445650

SCHEMBL445650

O=C(O)c1c2c(c3ccccc3c1C(=O)O)C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 5/20 0.44
KMT2A Q03164 4/20 0.44
GLA P06280 3/20 0.44
MEN1 O00255 3/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
TYMS P04818 1/20 0.40
LMNA P02545 2/20 0.39
GAA P10253 2/20 0.38
TSHR P16473 1/20 0.38
TTR P02766 1/20 0.38
WDR5 P61964 1/20 0.37
USP2 O75604 1/20 0.37
CSNK2A2 P19784 1/20 0.37
PTGS1 P23219 1/20 0.37
CSNK2B P67870 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401930 0.85 ALDH1A1 (0.42) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL6054743 0.83 KDM4E (0.42) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL3304903 0.80 KDM4E (0.40) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL1077861 0.80 ALDH1A1 (0.38) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL31634630 0.80 ALDH1A1 (0.38) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL25177897 0.78 KDM4E (0.60) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL6392102 0.78 ALOX15 (0.48) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL54422 0.78 KDM4E (0.58) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL21879686 0.78 LMNA (0.51) KDM4ETDP1ALDH1A1KMT2AGLA
SCHEMBL8850931 0.78 KMT2A (0.45) KDM4ETDP1ALDH1A1KMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 559 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115594967-B Long carbon chain polyamide foaming material and preparation method thereof 北京化工大学 2024-03-26 CN claimed
CN-115093566-B Covalent organic framework material with electrochromic property and preparation method thereof 闽都创新实验室 2024-03-01 CN claimed
CN-117497881-A Construction method of water-based manganese-covalent organic framework battery 兰州城市学院 2024-02-02 CN claimed
CN-117414424-A Preparation method of photosensitizer based on naphthalene dianhydride small molecule 浙江工业大学 2024-01-19 CN claimed
WO-2023242722-A1 GREASE THICKENING AGENT INV NYLON CHEMICALS AMERICAS, LLC (US) 2023-12-21 WO claimed
CN-113649045-B Modified titanium nitride nanotube with Ni-MOF as precursor and preparation method and application thereof 广东工业大学 2023-12-08 CN claimed
CN-115353091-B Hard carbon negative electrode material and preparation method and application thereof 广东东岛新能源股份有限公司 2023-12-08 CN claimed
CN-117186367-A High molecular weight glycolide/caprolactone random copolymer and preparation method thereof 中国神华煤制油化工有限公司 2023-12-08 CN claimed
CN-116694032-A Photochromic master batch and preparation method and application thereof 苏州宝丽迪材料科技股份有限公司 2023-09-05 CN claimed
CN-113149465-B Preparation method of porous electrochromic glass 广东科迪微晶玻璃实业有限公司 2023-08-29 CN claimed
WO-2013028232-A1 PHOTODETECTOR AND UPCONVERSION DEVICE WITH GAIN (EC) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2013-02-28 WO claimed
WO-2013003850-A2 A METHOD AND APPARATUS FOR DETECTING INFRARED RADIATION WITH GAIN UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) 2013-01-03 WO claimed
US-20120118363-A1 ORGANIC SEMICONDUCTORS AS WINDOW LAYERS FOR INORGANIC SOLAR CELLS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2012-05-17 US claimed
WO-2012037260-A1 ORGANIC SEMICONDUCTORS AS WINDOW LAYERS FOR INORGANIC SOLAR CELLS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2012-03-22 WO claimed
EP-2377180-A2 ENHANCEMENT OF ORGANIC PHOTOVOLTAIC CELL OPEN CIRCUIT VOLTAGE USING ELECTRON/HOLE BLOCKING EXCITON BLOCKING LAYERS The Regents of the University of Michigan (US) 2011-10-19 EP claimed
US-20110012091-A1 ENHANCEMENT OF ORGANIC PHOTOVOLTAIC CELL OPEN CIRCUIT VOLTAGE USING ELECTRON/HOLE BLOCKING EXCITON BLOCKING LAYERS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2011-01-20 US claimed
WO-2010120393-A2 ENHANCEMENT OF ORGANIC PHOTOVOLTAIC CELL OPEN CIRCUIT VOLTAGE USING ELECTRON/HOLE BLOCKING EXCITON BLOCKING LAYERS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2010-10-21 WO claimed
US-7220986-B2 Photoelectric current multiplier using molecular crystal and production method therefor JAPAN SCIENCE & TECHNOLOGY AGENCY (JP) 2007-05-22 US claimed
US-20040256554-A1 Photoelectric current multiplier using molecular crystal and production method therefor JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2004-12-23 US claimed
EP-0415447-A1 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP claimed