SCHEMBL6392102

SCHEMBL6392102

O=C1OC(=O)c2c1c1ccccc1c1ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
GPR84 Q9NQS5 1/20 0.41
ALDH1A1 P00352 5/20 0.40
HPGD P15428 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
KDM4E B2RXH2 3/20 0.40
HSD17B10 Q99714 2/20 0.40
MAOA P21397 2/20 0.40
GLA P06280 2/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
PGAM1 P18669 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
TSHR P16473 2/20 0.39
PAX8 Q06710 1/20 0.39
MAPK1 P28482 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10771120 0.81 ALDH1A1 (0.58) ALOX15TDP1ALDH1A1HPGDSMN1; SMN2
SCHEMBL503033 0.81 TSHR (0.58) ALOX15TDP1GPR84ALDH1A1HPGD
SCHEMBL10729627 0.81 MAOA (0.51) TDP1ALDH1A1KDM4EMAOAMAPT
SCHEMBL15119598 0.79 MAPT (0.50) ALOX15TDP1GPR84ALDH1A1HPGD
SCHEMBL10012405 0.79 HSD17B10 (0.41) ALOX15TDP1ALDH1A1HPGDSMN1; SMN2
SCHEMBL445650 0.78 KDM4E (0.46) TDP1ALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL10733687 0.77 TTR (0.55) ALDH1A1KDM4EHSD17B10KMT2ATP53
SCHEMBL10080464 0.77 MAPT (0.55) TDP1ALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL13014974 0.77 TTR (0.55) ALDH1A1KDM4EHSD17B10KMT2ATP53
SCHEMBL13415489 0.76 ALOX15 (0.42) ALOX15TDP1ALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9671688-B2 Monomer for hardmask composition, hardmask composition including said monomer, and method for forming pattern using said hardmask composition CHEIL INDUSTRIES, INC. (KR) 2017-06-06 US disclosed
US-9671688-B2 Monomer for hardmask composition, hardmask composition including said monomer, and method for forming pattern using said hardmask composition CHEIL INDUSTRIES, INC. (KR) 2017-06-06 US disclosed
US-20150301446-A1 MONOMER FOR HARDMASK COMPOSITION, HARDMASK COMPOSITION INCLUDING SAID MONOMER, AND METHOD FOR FORMING PATTERN USING SAID HARDMASK COMPOSITION CHEIL INDUSTRIES INC. (KR) 2015-10-22 US disclosed
US-8888906-B2 Heat-sensitive color-developing composition and heat-sensitive recording material comprising the composition YAMAMOTO CHEMICALS, INC. (JP) 2014-11-18 US disclosed
US-8888906-B2 Heat-sensitive color-developing composition and heat-sensitive recording material comprising the composition YAMAMOTO CHEMICALS, INC. (JP) 2014-11-18 US disclosed
EP-2617578-A1 HEAT-SENSITIVE CHROMOGENIC COMPOSITION AND HEAT-SENSITIVE RECORDING MATERIAL FORMED USING SAID COMPOSITION Yamamoto Chemicals, Inc. (JP) 2013-07-24 EP disclosed
US-20130180430-A1 HEAT-SENSITIVE COLOR-DEVELOPING COMPOSITION AND HEAT-SENSITIVE RECORDING MATERIAL COMPRISING THE COMPOSITION YAMAMOTO CHEMICALS, INC. (JP) 2013-07-18 US disclosed
US-20130180430-A1 HEAT-SENSITIVE COLOR-DEVELOPING COMPOSITION AND HEAT-SENSITIVE RECORDING MATERIAL COMPRISING THE COMPOSITION YAMAMOTO CHEMICALS, INC. (JP) 2013-07-18 US disclosed
CN-102405267-A Aziridine crosslinking agents for acrylic adhesives 3M INNOVATIVE PROPERTIES CO 2012-04-04 CN disclosed
US-6960667-B2 Fluorescent maleimides and uses thereof CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-01 US disclosed
US-20030189191-A1 Fluorescent maleimides and uses thereof KUNIMOTO KAZUHIKO (JP) 2003-10-09 US disclosed
US-6508957-B2 Ultraviolet fluorescent material for void detection and for preparation of scintillators, films, luminescent solar energy collectors, organic electroluminescent devices, printing inks, electrophotographic toners CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-21 US disclosed
EP-1216285-A1 FLUORESCENT MALEIMIDES AND USES THEREOF Ciba SC Holding AG (CH) 2002-06-26 EP disclosed
US-20020065422-A1 Fluorescent maleimides and uses thereof KUNIMOTO KAZUHIKO (JP) 2002-05-30 US disclosed
US-6258954-B1 ELECTROLUMINESCENCE; DETECTION VOIDS CIBA SPECIALTY CHEMICALS CORP. 2001-07-10 US disclosed
WO-2001019939-A1 FLUORESCENT MALEIMIDES AND USES THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-03-22 WO disclosed
US-4638072-A POLYAMIDES, POLYIMIDES STANDARD OIL COMPANY (INDIANA) (US) 1987-01-20 US disclosed
US-4596867-A Disubstituted maleic anhydride compounds STANDARD OIL COMPANY (INDIANA) (US) 1986-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065422-A1 Fluorescent maleimides and uses thereof IK, PAH, MYO1F ALOX15 4841/4885TDP1 455/4885GPR84 3333/4885
US-20030189191-A1 Fluorescent maleimides and uses thereof CBR1, CBR3, MT-CO2 ALOX15 3581/4885TDP1 1058/4885GPR84 3077/4885
US-20150301446-A1 MONOMER FOR HARDMASK COMPOSITION, HARDMASK COMPOSITION INCLUDING SAID MONOMER, AND METHOD FOR FORMING PATTERN USING SAID HARDMASK COMPOSITION MLX, ACTN1, LIMA1 ALOX15 441/4885TDP1 2583/4885GPR84 3380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.