SCHEMBL4456529

SCHEMBL4456529

O=C(O)C=CCC(CC(=O)O)C(O)=S

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.37
▸ GABRR1 P24046 2/20 0.37
▸ GABRR2 P28476 2/20 0.37
▸ BLM P54132 2/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ GABRR3 A8MPY1 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ APEX1 P27695 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ FOLH1 Q04609 2/20 0.33
▸ SLC22A6 Q4U2R8 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ EGLN1 Q9GZT9 1/20 0.31
▸ EGLN3 Q9H6Z9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8815418 0.83 FOLH1 (0.45) TSHRGABRR1GABRR2BLMTDP1
SCHEMBL6556587 0.80 FOLH1 (0.33) TDP1FOLH1SLC22A6
SCHEMBL8979306 0.75 GRIK1 (0.42) TDP1FOLH1SLC22A6
SCHEMBL4890978 0.75 FOLH1 (0.46) TSHRGABRR1TDP1LMNAFOLH1
SCHEMBL11855398 0.71 TSHR (0.39) TSHRGABRR1GABRR2BLMTDP1
SCHEMBL11855406 0.71 TSHR (0.39) TSHRGABRR1GABRR2BLMTDP1
SCHEMBL4890967 0.69 FOLH1 (0.41) TSHRGABRR1TDP1LMNAFOLH1
SCHEMBL1502606 0.68 FOLH1 (0.52) TSHRGABRR1GABRR2BLMTDP1
SCHEMBL11203330 0.67 MMP2 (0.40) TSHRTDP1FOLH1SLC22A6
SCHEMBL516283 0.67 CA2 (0.43) TSHRGABRR1GABRR2BLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999684-B Soil conditioning composition and preparation method thereof 三友生物(烟台)有限公司 2023-06-16 — — CN claimed
CN-113999684-A Soil conditioning composition and preparation method thereof 三友生物(烟台)有限公司 2022-02-01 — — CN claimed
CN-110550750-A Traceable phosphorus-free corrosion and scale inhibitor special for oxygen plant SMEDIC CO LTD 2019-12-10 — — CN claimed
US-5922910-A Synthesis of carboxyalkylthiosuccinic acids ELF ATOCHEM S.A. (FR) 1999-07-13 — — US claimed
JP-10168482-A — — None — — JP disclosed
JP-10110186-A — — None — — JP disclosed
JP-11130747-A — — None — — JP disclosed
CN-113999684-B Soil conditioning composition and preparation method thereof 三友生物(烟台)有限公司 2023-06-16 — — CN disclosed
CN-113999684-A Soil conditioning composition and preparation method thereof 三友生物(烟台)有限公司 2022-02-01 — — CN disclosed
CN-110550750-A Traceable phosphorus-free corrosion and scale inhibitor special for oxygen plant SMEDIC CO LTD 2019-12-10 — — CN disclosed
CN-110550750-A Traceable phosphorus-free corrosion and scale inhibitor special for oxygen plant SMEDIC CO LTD 2019-12-10 — — CN disclosed
US-9433216-B2 Construction material preservative NIPPON SODA CO., LTD. (JP) 2016-09-06 — — US disclosed
US-20060185544-A1 Method for replenishing development replenisher in automatic developing machine for photosensitive lithographic printing plate precursor and automatic photosensitive lithographic printing plate precursor developing machine FUJI PHOTO FILM CO., LTD. (JP) 2006-08-24 — — US disclosed
US-5922910-A Synthesis of carboxyalkylthiosuccinic acids ELF ATOCHEM S.A. (FR) 1999-07-13 — — US disclosed
US-5922910-A Synthesis of carboxyalkylthiosuccinic acids ELF ATOCHEM S.A. (FR) 1999-07-13 — — US disclosed
JP-H11130747-A SYNTHESIS OF CARBOXYALKYLTHIOSUCCINATE SOC NATL ELF AQUITAINE <SNEA> 1999-05-18 — — JP disclosed
CN-1210854-A Synthesis of carboxylalkyl thiosuccnic acid ELF AQUITAINE EXPLORATION PROD (FR) 1999-03-17 — — CN disclosed
EP-0899257-A1 Process for the preparation of carboxyalkylthiosuccinic acids ELF ATOCHEM S.A. (FR) 1999-03-03 — — EP disclosed
JP-H10168482-A DETERGENT COMPOSITION NOF CORP 1998-06-23 — — JP disclosed
JP-H10110186-A DETERGENT COMPOSITION NOF CORP 1998-04-28 — — JP disclosed
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