Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21425786 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1TRPA1TSHRHDAC8 | |
| SCHEMBL7581073 | 0.77 | NR1H2 (0.43) | ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL4757844 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| SCHEMBL13481477 | 0.73 | MAOA (0.45) | ALDH1A1TRPA1 | |
| SCHEMBL7297682 | 0.73 | CYP3A4 (0.46) | ALDH1A1TDP1TSHRHSD17B10TP53 | |
| Methyl Alcohol SCHEMBL28639806 | 0.72 | ALDH1A1 (0.79) | ALDH1A1TDP1TRPA1TSHRHDAC8 | |
| SCHEMBL98657 | 0.72 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8 | |
| SCHEMBL95522 | 0.72 | LMNA (0.42) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18649595 | 0.72 | ALDH1A1 (0.58) | ALDH1A1TDP1TRPA1TSHRHDAC8 | |
| SCHEMBL10716957 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TDP1TSHRHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1524289-B1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-20070149639-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | HORIKOSHI HIROSHI | 2007-06-28 | — | — | US | disclosed |
| EP-1524289-A1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |