SCHEMBL98657

SCHEMBL98657

C=Cc1ccc(SC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
CYP1A1 P04798 8/20 0.48
CYP1A2 P05177 8/20 0.48
CYP1B1 Q16678 8/20 0.48
FBP1 P09467 1/20 0.45
TSHR P16473 1/20 0.43
HDAC8 Q9BY41 1/20 0.42
XDH P47989 1/20 0.42
GSK3B P49841 1/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16709773 0.93 ALDH1A1 (0.52) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL13790333 0.78 CYP1A1 (0.71) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL1024003 0.78 ALDH1A1 (0.65) ALDH1A1TSHRHDAC8LMNA
SCHEMBL7567897 0.78 CYP1A1 (0.71) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL13790243 0.78 CYP1A1 (0.71) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL4252557 0.78 ALDH1A1 (0.65) ALDH1A1TSHRHDAC8KMT2AMAPT
SCHEMBL8367958 0.78 CYP1A1 (0.71) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL11613661 0.78 ALDH1A1 (0.64) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL8546043 0.77 CYP1A1 (0.52) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL8546041 0.77 CYP1A1 (0.52) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684346-A Preparation method of selective beta-silicon-based aryl acetic acid compound 扬州大学 2025-03-25 CN claimed
CN-115819649-A Polymerization preparation method of polystyrene derivative 南阳森源塑胶有限公司 2023-03-21 CN claimed
CN-111801358-B Method for producing polymer and flow reaction system for producing polymer 富士胶片株式会社 2022-12-16 CN claimed
CN-113061203-B Catalyst and preparation method thereof, and preparation method of styrene monomer isotactic polymer 中国科学院长春应用化学研究所 2022-03-29 CN claimed
CN-111269343-B High molecular weight and ultrahigh molecular weight maleic anhydride-styrene monomer alternating copolymer and preparation method thereof 中国科学院长春应用化学研究所 2021-08-17 CN claimed
CN-113061203-A Catalyst and preparation method thereof, and preparation method of styrene monomer isotactic polymer 中国科学院长春应用化学研究所 2021-07-02 CN claimed
CN-108530453-B 2(3) -p-methylthio styryl benzofuran quinoline derivative and preparation method and application thereof 中山大学 2021-05-11 CN claimed
CN-111269343-A High molecular weight and ultrahigh molecular weight maleic anhydride-styrene monomer alternating copolymer and preparation method thereof 中国科学院长春应用化学研究所 2020-06-12 CN claimed
JP-4351672-A None JP disclosed
JP-8217810-A None JP disclosed
US-12629382-B2 Therapy VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2026-05-19 US disclosed
US-12460039-B2 Block copolymer intermediate, block copolymer, and methods for producing same DIC CORPORATION (JP) 2025-11-04 US disclosed
CN-116082550-B Cycloolefin copolymer based on dicyclopentadiene and preparation method thereof 中国科学院长春应用化学研究所 2025-06-24 CN disclosed
CN-120192457-A Rare earth polydiene rubber with polystyrene-based polymer micro-block at chain head end, and preparation method and application thereof 青岛科技大学 2025-06-24 CN disclosed
US-4769369-A Anti-allergy 1(2H)-phthalazinones PENNWALT CORPORATION (US) 1988-09-06 US disclosed
EP-0202760-A2 Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-11-26 EP disclosed
EP-0193013-A2 Benzimidazolyl-pyridazinones MERCK PATENT GmbH (DE) 1986-09-03 EP disclosed
US-4029706-A Reduction with polymeric reagent DYNAPOL (US) 1977-06-14 US disclosed
US-4000201-A ALKYL ETHER, CROSSLINKED SULFIDE POLYMER DYNAPOL CORPORATION (US) 1976-12-28 US disclosed
US-3959190-A ALKYL SULFIDE- CROSSLINKED POLYSTYRENE DYNAPOL (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629382-B2 Therapy NR3C1, MGMT, GRM3 ALDH1A1 338/4885CYP1A1 899/4885CYP1A2 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.