Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CTSL | P07711 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558354 | 0.79 | CTSS (0.45) | CTSSCTSLPOLBHCRTR1KIT | |
| SCHEMBL4457090 | 0.77 | CTSS (0.43) | CTSSCTSLHCRTR1KITDDR2 | |
| SCHEMBL4463467 | 0.76 | CTSL (0.46) | CTSSCTSLHCRTR1KITDDR2 | |
| SCHEMBL13606505 | 0.72 | CTSL (0.43) | CTSSCTSLPOLBHCRTR1KIT | |
| SCHEMBL4458411 | 0.69 | CTSL (0.44) | CTSSCTSLHCRTR1KITDDR2 | |
| SCHEMBL4458412 | 0.69 | CTSL (0.44) | CTSSCTSLHCRTR1KITDDR2 | |
| SCHEMBL4469679 | 0.69 | CTSL (0.43) | CTSSCTSLHCRTR1KITDDR2 | |
| SCHEMBL4469682 | 0.69 | CTSL (0.43) | CTSSCTSLHCRTR1KITDDR2 | |
| SCHEMBL4457207 | 0.67 | ELANE (0.52) | CTSSMEN1ALDH1A1KMT2A | |
| SCHEMBL4453282 | 0.64 | NPC1 (0.43) | CTSSMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |