Trifluoromethanesulfonamide

Trifluoromethanesulfonamide

SCHEMBL4457463

CCCC[N+](C)(C)C.NS(=O)(=O)C(F)(F)F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.46
CA1 P00915 3/20 0.46
CA7 P43166 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
DNM1 Q05193 7/20 0.44
APAF1 O14727 1/20 0.41
HSP90AA1 P07900 1/20 0.41
RAD52 P43351 1/20 0.41
EPHX1 P07099 1/20 0.41
BBOX1 O75936 1/20 0.39
ENPP2 Q13822 3/20 0.39
MEN1 O00255 2/20 0.35
NFKB1 P19838 2/20 0.35
KMT2A Q03164 2/20 0.35
APEX1 P27695 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
ACHE P22303 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonamide SCHEMBL1702592 0.92 DNM1 (0.58) CA2CA1CA7CA13DNM1
Trifluoromethanesulfonamide SCHEMBL6436451 0.92 DNM1 (0.58) CA2CA1CA7CA13DNM1
Tributylmethylammonium SCHEMBL28981157 0.88 CA2 (0.46) CA2CA1CA7CA13DNM1
Trifluoromethanesulfonamide SCHEMBL4359429 0.87 CA2 (0.50) CA2CA1CA7CA13DNM1
Trifluoromethanesulfonic Acid SCHEMBL10660719 0.83 BBOX1 (0.48) DNM1APAF1HSP90AA1RAD52EPHX1
Trifluoromethanesulfonic Acid SCHEMBL10660726 0.83 DNM1 (0.44) DNM1APAF1HSP90AA1RAD52EPHX1
Trifluoromethanesulfonamide SCHEMBL3315782 0.82 CA2 (0.44) CA2CA1CA7CA13BBOX1
SCHEMBL28176552 0.81 DNM1 (0.48) CA2DNM1APAF1HSP90AA1RAD52
SCHEMBL28177458 0.81 DNM1 (0.48) CA2DNM1APAF1HSP90AA1RAD52
SCHEMBL925224 0.80 DNM1 (0.41) DNM1APAF1HSP90AA1RAD52EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9452425-B2 Compositions containing ionic liquids and their uses, in particular in organic synthesis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-09-27 US disclosed
US-20090326228-A1 COMPOSITIONS CONTAINING IONIC LIQUIDS AND THEIR USES, IN PARTICULAR IN ORGANIC SYNTHESIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-12-31 US disclosed
US-20060128996-A1 Compositions containing Ionic liquids and uses thereof, especially in organic synthesis UNIVERSITE DE RENNES 1 (FR) 2006-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128996-A1 Compositions containing Ionic liquids and uses thereof, especially in organic synthesis F12, ANXA1, OLA1 CA2 182/4885CA1 78/4885CA7 656/4885
US-20090326228-A1 COMPOSITIONS CONTAINING IONIC LIQUIDS AND THEIR USES, IN PARTICULAR IN ORGANIC SYNTHESIS F12, ANXA1, F11 CA2 209/4885CA1 79/4885CA7 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.