Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774399 | 0.81 | GABRA1 (0.48) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL4629018 | 0.80 | KEAP1 (0.55) | CASP3SENP7SENP6MAPTALDH1A1 | |
| SCHEMBL15392669 | 0.77 | KEAP1 (0.48) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL4449942 | 0.76 | ALDH1A1 (0.52) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL18985787 | 0.76 | MAPT (0.60) | MAPTALDH1A1PKMLMNAKMT2A | |
| SCHEMBL24259133 | 0.76 | KEAP1 (0.53) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL4720647 | 0.76 | KEAP1 (0.55) | CASP3SENP7MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6738366 | 0.75 | TSHR (0.76) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30461135 | 0.75 | RAB9A (0.69) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL30461136 | 0.75 | RAB9A (0.69) | CASP3SENP8SENP7SENP6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228547-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-11-03 | — | — | WO | disclosed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |