Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947384 | 0.84 | ALDH1A1 (0.33) | NPSR1TSHRTP53 | |
| SCHEMBL4452162 | 0.84 | L3MBTL1 (0.38) | MAPTL3MBTL1NPSR1GABRA1GABRB2 | |
| SCHEMBL4455343 | 0.84 | CYP4F2 (0.34) | MAPTL3MBTL1NPSR1CYP4F2CYP4A11 | |
| SCHEMBL4455991 | 0.81 | LIPG (0.40) | CYP4F2CYP4A11CYP2D6 | |
| SCHEMBL4461175 | 0.81 | L3MBTL1 (0.40) | MAPTL3MBTL1NPSR1TSHRHPGD | |
| SCHEMBL4460493 | 0.81 | GABRA1 (0.38) | MAPTL3MBTL1NPSR1GABRA1GABRB2 | |
| SCHEMBL4448593 | 0.77 | MAPT (0.36) | MAPTL3MBTL1NPSR1GABRA1GABRB2 | |
| SCHEMBL4458090 | 0.77 | TSHR (0.38) | MAPTTSHR | |
| SCHEMBL1726433 | 0.76 | GABRA1 (0.34) | MAPTL3MBTL1NPSR1GABRA1GABRB2 | |
| SCHEMBL10742274 | 0.75 | ALDH1A1 (0.45) | MAPTL3MBTL1NPSR1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612148-B2 | Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2009-11-03 | — | — | US | disclosed |
| US-20080146733-A1 | Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2008-06-19 | — | — | US | disclosed |
| US-4743687-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1988-05-10 | — | — | US | disclosed |