SCHEMBL4458207

SCHEMBL4458207

CN(C)C(=O)N[C@@H](CSN=O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
CAPN1 P07384 1/20 0.34
FOLH1 Q04609 3/20 0.32
NAALAD2 Q9Y3Q0 3/20 0.32
RIMKLA Q8IXN7 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
NFKB1 P19838 1/20 0.32
PTGS2 P35354 1/20 0.32
THPO P40225 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ITGA4 P13612 2/20 0.31
ITGB7 P26010 1/20 0.31
ACE P12821 1/20 0.31
TGFBR1 P36897 1/20 0.31
ITGB1 P05556 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4457104 1.00 ALDH1A1 (0.35) ALDH1A1CAPN1FOLH1NAALAD2RIMKLA
SCHEMBL4457105 1.00 ALDH1A1 (0.35) ALDH1A1CAPN1FOLH1NAALAD2RIMKLA
SCHEMBL221191 0.80 MAPT (0.52) ALDH1A1FOLH1NAALAD2RIMKLAKDM4E
SCHEMBL221192 0.80 MAPT (0.52) ALDH1A1FOLH1NAALAD2RIMKLAKDM4E
SCHEMBL4456772 0.80 MAPT (0.52) ALDH1A1FOLH1NAALAD2RIMKLAKDM4E
SCHEMBL4461437 0.77 TGFBR1 (0.37) FOLH1NAALAD2RIMKLAKDM4EMAPT
SCHEMBL4462156 0.77 TGFBR1 (0.37) FOLH1NAALAD2RIMKLAKDM4EMAPT
SCHEMBL4469725 0.77 NOD1 (0.38) ALDH1A1FOLH1NAALAD2RIMKLAKDM4E
Acetylcysteine SCHEMBL4428940 0.73 MAPT (0.68) ALDH1A1FOLH1KDM4EMAPTTHRB
Acetylcysteine SCHEMBL4428938 0.73 MAPT (0.68) ALDH1A1FOLH1KDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009151744-A1 S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES GALLEON PHARMACEUTICALS, INC. (US) 2009-12-17 WO claimed
WO-2009151744-A1 S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES GALLEON PHARMACEUTICALS, INC. (US) 2009-12-17 WO disclosed