Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.32 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221191 | 0.81 | MAPT (0.52) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL221192 | 0.81 | MAPT (0.52) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL4456772 | 0.81 | MAPT (0.52) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL4955697 | 0.81 | NOD1 (0.42) | NOD1CYP2C9PIN1CA2CA4 | |
| SCHEMBL4907662 | 0.81 | ITGB1 (0.45) | NOD1CYP2C9PIN1CA2CA4 | |
| SCHEMBL4462156 | 0.79 | TGFBR1 (0.37) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL4461437 | 0.79 | TGFBR1 (0.37) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL4953665 | 0.78 | NOD1 (0.40) | NOD1CYP2C9PIN1CA2CA4 | |
| SCHEMBL4458207 | 0.77 | ALDH1A1 (0.35) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL4457104 | 0.77 | ALDH1A1 (0.35) | FOLH1NAALAD2RIMKLAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |