Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13672318 | 0.84 | NPC1 (0.44) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4467507 | 0.74 | NPC1 (0.39) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20480462 | 0.73 | ALDH1A1 (0.62) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30506306 | 0.73 | ALDH1A1 (0.62) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL29982814 | 0.72 | MAOA (0.40) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9818795 | 0.70 | MAPT (0.61) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL21623581 | 0.68 | KDM4E (0.52) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1146705 | 0.67 | ALDH1A1 (1.00) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20116002 | 0.66 | ALDH1A1 (0.74) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4686035 | 0.65 | GPR35 (0.41) | KMT2AALDH1A1MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598403-B2 | Synthesis of chromanones | THE UNIVERSITY OF SOUTH CAROLINA RESEARCH FOUNDATION (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598403-B2 | Synthesis of chromanones | THE UNIVERSITY OF SOUTH CAROLINA RESEARCH FOUNDATION (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598403-B2 | Synthesis of chromanones | THE UNIVERSITY OF SOUTH CAROLINA RESEARCH FOUNDATION (US) | 2009-10-06 | — | — | US | disclosed |
| US-20070203214-A1 | Synthesis Of Chromanones | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203214-A1 | Synthesis Of Chromanones | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203214-A1 | Synthesis Of Chromanones | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-08-30 | — | — | US | disclosed |
| WO-2004103985-A2 | DERIVATIVES OF FUSAROCHROMANONE AS THERAPEUTIC AGENTS | UNIVERSITY OF SOUTH CAROLINA (US) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203214-A1 | Synthesis Of Chromanones | MAP3K6, MAP3K8, MAP3K1 | RAB9A 3243/4885NPC1 2619/4885KMT2A 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.