Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458303 | 1.00 | TRPV1 (0.61) | TRPV1NPC1LMNACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4780345 | 0.80 | TRPV1 (0.56) | TRPV1CYP3A4 | |
| SCHEMBL4781057 | 0.78 | TRPV1 (0.55) | TRPV1CYP3A4 | |
| SCHEMBL4472454 | 0.77 | ALDH1A1 (0.46) | TRPV1NPC1HPGDRAB9A | |
| SCHEMBL13783798 | 0.77 | ALDH1A1 (0.46) | TRPV1NPC1HPGDRAB9A | |
| SCHEMBL4472460 | 0.77 | ALDH1A1 (0.46) | TRPV1NPC1HPGDRAB9A | |
| Trifluoroacetic Acid SCHEMBL4777995 | 0.77 | TRPV1 (0.52) | TRPV1CYP3A4 | |
| SCHEMBL4779535 | 0.77 | TRPV1 (0.43) | TRPV1NPC1RAB9A | |
| SCHEMBL13783960 | 0.77 | NPC1 (0.41) | NPC1HTTRAB9A | |
| SCHEMBL4451787 | 0.76 | HCRTR1 (0.40) | NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |