Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900718 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1GAAKMT2ABCAT2 | |
| SCHEMBL8945914 | 0.83 | ALDH1A1 (0.79) | ALDH1A1TDP1GAAKMT2AMAPT | |
| SCHEMBL4192923 | 0.82 | BCAT2 (0.46) | ALDH1A1TDP1GAAKMT2ABCAT2 | |
| SCHEMBL3831520 | 0.82 | BCAT2 (0.46) | ALDH1A1TDP1GAAKMT2ABCAT2 | |
| SCHEMBL5968855 | 0.81 | IRAK4 (0.47) | ALDH1A1TDP1GAAKMT2ABCAT2 | |
| SCHEMBL6266294 | 0.81 | IRAK4 (0.47) | ALDH1A1TDP1GAAKMT2ABCAT2 | |
| SCHEMBL22032854 | 0.81 | BCAT2 (0.44) | ALDH1A1TDP1GAAKMT2ABCAT2 | |
| SCHEMBL28722647 | 0.81 | BCAT2 (0.44) | ALDH1A1TDP1GAAKMT2ABCAT2 | |
| SCHEMBL3663651 | 0.81 | IRAK4 (0.47) | ALDH1A1TDP1GAAKMT2ABCAT2 | |
| SCHEMBL28801273 | 0.81 | BCAT2 (0.44) | ALDH1A1TDP1GAAKMT2ABCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| CN-106565517-B | A method of amide is prepared by arylmethane derivative and nitrile | 湖南大学 | 2018-08-17 | — | — | CN | disclosed |
| CN-107790186-A | A kind of new decamethyl Zirconocenes and its preparation method and application | 山西医科大学 | 2018-03-13 | — | — | CN | disclosed |
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |