Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905225 | 0.86 | KMT2A (0.46) | NPSR1L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL398536 | 0.86 | NPSR1 (0.44) | NPSR1L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL3424139 | 0.84 | SMN1; SMN2 (0.44) | NPSR1L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL5141689 | 0.83 | NPSR1 (0.46) | NPSR1L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL402771 | 0.83 | NPSR1 (0.41) | NPSR1L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL400582 | 0.82 | NPSR1 (0.44) | NPSR1L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL4657473 | 0.78 | ALDH1A1 (0.58) | NPSR1L3MBTL1ALDH1A1KMT2APOLB | |
| SCHEMBL2404029 | 0.76 | NPSR1 (0.45) | NPSR1L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL19778 | 0.75 | NPSR1 (0.70) | NPSR1L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL10418486 | 0.74 | POLB (0.40) | NPSR1L3MBTL1ATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |