SCHEMBL4459045

SCHEMBL4459045

CC1(C)CC2(CC(C)(C)c3cc(OCCCl)c(O)cc32)c2cc(O)c(OCCCl)cc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.33
RXRA P19793 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4464095 0.94 RXRA (0.33) OPRM1RXRA
SCHEMBL4474023 0.87 RXRA (0.41) RXRA
SCHEMBL4455722 0.85 OPRM1 (0.42) OPRM1RXRA
SCHEMBL4466037 0.84 OPRM1 (0.37) OPRM1RXRA
SCHEMBL8019962 0.83 HNF4A (0.41) RXRA
SCHEMBL4463620 0.83 RXRA (0.43) RXRA
SCHEMBL4459350 0.83 DRD1 (0.36) OPRM1RXRA
SCHEMBL4461726 0.83 RXRA (0.43) RXRA
SCHEMBL4460088 0.83 RXRA (0.43) RXRA
SCHEMBL4467219 0.82 DRD1 (0.35) OPRM1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed