SCHEMBL4459202

SCHEMBL4459202

Cc1c(C)c2c(c(C)c1O)CCC(=O)O2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX5 P09917 4/20 0.35
SRC P12931 2/20 0.34
NUAK1 O60285 1/20 0.34
IGF1R P08069 1/20 0.34
MET P08581 1/20 0.34
PIM1 P11309 1/20 0.34
AXL P30530 1/20 0.34
AKT1 P31749 1/20 0.34
KDR P35968 1/20 0.34
NEK2 P51955 1/20 0.34
PLK1 P53350 1/20 0.34
PTK2 Q05397 1/20 0.34
PKN1 Q16512 1/20 0.34
AURKB Q96GD4 1/20 0.34
NEK6 Q9HC98 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12465650 0.84 TSHR (0.33) TSHRPTGS1PTGS2CYP1A2CYP3A4
SCHEMBL3145048 0.80 PTGS1 (0.44) TSHRPTGS1PTGS2CYP1A2CYP3A4
SCHEMBL23421679 0.78 PTGS2 (0.45) TSHRPTGS1PTGS2SRCNUAK1
SCHEMBL13592921 0.77 PTGS1 (0.41) TSHRPTGS1PTGS2CYP1A2CYP3A4
SCHEMBL6906681 0.73 ALOX5 (0.41) TSHRPTGS1PTGS2CYP1A2CYP3A4
SCHEMBL14026631 0.69 KDM4E (0.38) TSHRCYP1A2CYP2C9CYP2C19
SCHEMBL4466134 0.68
SCHEMBL9197687 0.68 PTGS2 (0.40) PTGS1PTGS2SRCNUAK1IGF1R
SCHEMBL10058464 0.67 AKT1 (0.39) TSHRCYP3A4ALOX5AKT1MAPT
SCHEMBL13431163 0.67 ALOX5 (0.36) TSHRPTGS1PTGS2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025237521-A1 A NOVEL WATER-PROCESSABLE N-TYPE CONDUCTING POLYMER WESTRA MATERIALS AB (SE) 2025-11-20 WO disclosed
EP-4630472-A1 A METHOD FOR OBTAINING A WATER-PROCESSABLE N-TYPE CONDUCTING POLYMER Westra Materials AB (SE) 2025-10-15 EP disclosed
WO-2024165720-A1 A METHOD FOR OBTAINING A WATER-PROCESSABLE N-TYPE CONDUCTING POLYMER N-INK AB (SE) 2024-08-15 WO disclosed
WO-2021106947-A1 NOVEL QUINONE DERIVATIVE AND ANTITRYPANOSOMAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT 国立大学法人群馬大学 2021-06-03 WO disclosed
WO-2012105857-A1 GEL ACTUATOR UNIVERSITY OF OTAGO (NZ) 2012-08-09 WO disclosed
US-7576094-B2 Spiro derivatives as lipoxygenase inhibitors ELI LILLY AND COMPANY (US) 2009-08-18 US disclosed
EP-1836183-A2 SPIRO DERIVATIVES AS LIPOXYGENASE INHIBITORS Galileo Pharmaceuticals, Inc. (US) 2007-09-26 EP disclosed
WO-2006065686-A2 SPIRO DERIVATIVES AS LIPOXYGENASE INHIBITORS GALILEO PHARMACEUTICALS, INC. (US) 2006-06-22 WO disclosed
US-20060128790-A1 Spiro derivatives as lipoxygenase inhibitors GALILEO PHARMACEUTICALS, INC. 2006-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128790-A1 Spiro derivatives as lipoxygenase inhibitors ALOX15B, ALOX5, ALOX15 TSHR 2301/4885PTGS1 24/4885PTGS2 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.