SCHEMBL4459306

SCHEMBL4459306

Clc1cc(Cl)c(-c2c(Cl)c(Cl)cc(Cl)c2Cl)c(Cl)c1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.59
ALDH1A1 P00352 2/20 0.47
TSHR P16473 7/20 0.46
HPGD P15428 6/20 0.46
HSD17B10 Q99714 6/20 0.46
MAPK1 P28482 3/20 0.46
AHR P35869 8/20 0.43
CASP1 P29466 1/20 0.43
HSP90AA1 P07900 2/20 0.39
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
AKR1B1 P15121 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
USP2 O75604 1/20 0.33
EGFR P00533 1/20 0.33
LMNA P02545 1/20 0.33
ESR1 P03372 1/20 0.33
ERBB2 P04626 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4448782 0.94 CYP3A4 (0.69) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL3889367 0.94 CYP3A4 (0.67) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL30621942 0.94 CYP3A4 (0.67) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4448471 0.87 CYP3A4 (0.67) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4452692 0.87 CYP3A4 (0.64) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL30621937 0.86 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4459037 0.86 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4452922 0.85 ALDH1A1 (0.61) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4456478 0.81 ALDH1A1 (0.65) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL23827191 0.79 CYP3A4 (0.47) CYP3A4ALDH1A1TSHRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-120073425-A Connector and communication equipment 华为技术有限公司 2025-05-30 CN disclosed
CN-119268898-A Dynamic torque sensor 广州市斯巴拓电子科技有限公司 2025-01-07 CN disclosed
WO-2025004236-A1 OPTICAL TRANSCEIVER 日本電信電話株式会社 2025-01-02 WO disclosed
WO-2024199324-A1 OPTICAL CHIP, PHOTOELECTRIC CONVERSION APPARATUS, CO-PACKAGED OPTICS CHIP AND OPTICAL COMMUNICATION DEVICE 华为技术有限公司 2024-10-03 WO disclosed
WO-2024198913-A1 OPTICAL CHIP, PACKAGING METHOD FOR OPTICAL CHIP, AND RELATED DEVICE 华为技术有限公司 2024-10-03 WO disclosed
CN-118732152-A Optical chip, photoelectric conversion device, photoelectric sealing chip and optical communication equipment 华为技术有限公司 2024-10-01 CN disclosed
CN-118732153-A Optical chip, packaging method of optical chip and related equipment 华为技术有限公司 2024-10-01 CN disclosed
CN-110719687-B Apparatus and method for improved network connection 迈络思科技有限公司 2024-09-27 CN disclosed
CN-117835064-A Lens position adjustment method, device, apparatus, storage medium and program product OPPO广东移动通信有限公司 2024-04-05 CN disclosed
CN-109491146-B Light-emitting module and manufacturing method thereof, direct type backlight module and display device 高创(苏州)电子有限公司 2022-04-26 CN disclosed
CN-216391049-U Intelligent household appliance IOT controller 深圳市宏微映控科技有限公司 2022-04-26 CN disclosed
WO-2022041253-A1 OPTOELECTRONIC APPARATUS AND OPTOELECTRONIC INTEGRATION METHOD 华为技术有限公司 2022-03-03 WO disclosed
EP-3959820-A1 INTEGRATED SMART HELMET AND METHODS AND SYSTEMS OF CONTROLLING SMART HELMET Venkata Jagannadha Rao, Anirudha Surabhi (IN) 2022-03-02 EP disclosed
EP-3942471-A1 SEMICONDUCTOR STORAGE DEVICE Kioxia Corporation (JP) 2022-01-26 EP disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed
US-6132561-A CONTACTING A CONTAMINATED SOIL SAMPLE WITH AN EXTRACTION MEDIUM OF A MIXTURE OF AN ALKANE AND A WATER MISCIBLE ALCOHOL, THEREAFTER SUBJECTING THE EXTRACTION MEDIUM CONTAINING THE HALOGENATED ORGANIC CONTAMINANTS TO IONIZING RADIATION TO WARPET, LLC 2000-10-17 US disclosed