SCHEMBL4452922

SCHEMBL4452922

Clc1cc(Cl)c(-c2c(Cl)cc(Cl)c(Cl)c2Cl)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 5/20 0.56
AHR P35869 7/20 0.55
TSHR P16473 8/20 0.50
HSD17B10 Q99714 7/20 0.50
HPGD P15428 6/20 0.50
MAPK1 P28482 3/20 0.50
RECQL P46063 3/20 0.48
CASP1 P29466 2/20 0.48
HSP90AA1 P07900 2/20 0.38
HSPA5 P11021 2/20 0.37
MEN1 O00255 2/20 0.37
EGFR P00533 2/20 0.37
LMNA P02545 2/20 0.37
ESR1 P03372 2/20 0.37
ERBB2 P04626 2/20 0.37
LCK P06239 2/20 0.37
PGR P06401 2/20 0.37
POLB P06746 2/20 0.37
HTR1A P08908 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3889367 0.91 CYP3A4 (0.67) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL30621942 0.91 CYP3A4 (0.67) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL4456478 0.85 ALDH1A1 (0.65) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL4459306 0.85 CYP3A4 (0.59) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL4448782 0.85 CYP3A4 (0.69) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL4458192 0.81 ALDH1A1 (0.59) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL4448496 0.81 CYP3A4 (0.48) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL4448731 0.81 ALDH1A1 (0.52) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL2937097 0.80 TSHR (0.67) ALDH1A1CYP3A4AHRTSHRHSD17B10
SCHEMBL4459037 0.78 CYP3A4 (0.50) ALDH1A1CYP3A4AHRTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-117375327-B Axial flux motor with position feedback under water 西湖大学 2024-03-22 CN disclosed
CN-117375327-A Axial flux motor with position feedback under water 西湖大学 2024-01-09 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed