SCHEMBL4456478

SCHEMBL4456478

Clc1cc(Cl)c(-c2c(Cl)c(Cl)cc(Cl)c2Cl)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
AHR P35869 7/20 0.57
TSHR P16473 7/20 0.50
HSD17B10 Q99714 7/20 0.50
HPGD P15428 6/20 0.50
CYP3A4 P08684 5/20 0.50
RECQL P46063 3/20 0.50
CASP1 P29466 2/20 0.50
MAPK1 P28482 3/20 0.46
MEN1 O00255 2/20 0.39
EGFR P00533 2/20 0.39
LMNA P02545 2/20 0.39
ESR1 P03372 2/20 0.39
ERBB2 P04626 2/20 0.39
LCK P06239 2/20 0.39
PGR P06401 2/20 0.39
POLB P06746 2/20 0.39
HTR1A P08908 2/20 0.39
ADRA2A P08913 2/20 0.39
ADORA3 P0DMS8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452692 0.87 CYP3A4 (0.64) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4452922 0.85 ALDH1A1 (0.61) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4458192 0.84 ALDH1A1 (0.59) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL2937097 0.83 TSHR (0.67) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4459306 0.81 CYP3A4 (0.59) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL560391 0.80 ALDH1A1 (0.86) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4448471 0.80 CYP3A4 (0.67) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL358001 0.79 ALDH1A1 (1.00) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL11686234 0.77 HSD17B10 (0.68) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4459067 0.77 ALDH1A1 (0.58) ALDH1A1AHRTSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed