SCHEMBL3889367

SCHEMBL3889367

Clc1cc(Cl)c(-c2c(Cl)cc(Cl)c(Cl)c2Cl)c(Cl)c1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.67
ALDH1A1 P00352 2/20 0.53
TSHR P16473 7/20 0.50
HPGD P15428 6/20 0.50
HSD17B10 Q99714 6/20 0.50
MAPK1 P28482 3/20 0.50
AHR P35869 8/20 0.48
CASP1 P29466 1/20 0.47
HSP90AA1 P07900 2/20 0.43
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
AKR1B1 P15121 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
USP2 O75604 1/20 0.36
EGFR P00533 1/20 0.36
LMNA P02545 1/20 0.36
ESR1 P03372 1/20 0.36
ERBB2 P04626 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30621942 1.00 CYP3A4 (0.67) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4459306 0.94 CYP3A4 (0.59) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4448782 0.94 CYP3A4 (0.69) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4452922 0.91 ALDH1A1 (0.61) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4459037 0.86 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL30621937 0.86 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL4448496 0.84 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRHPGDHSD17B10
SCHEMBL23827190 0.82 AHR (0.67) CYP3A4ALDH1A1TSHRHPGDHSD17B10
Pentachlorobenzene SCHEMBL11455164 0.81 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDHSD17B10
Pentachlorobenzene SCHEMBL183144 0.81 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090306452-A1 APPARATUS FOR TREATING A CONTAMINATED MEDIA WITH A SORBENT ARCADIS U.S., INC. 2009-12-10 US disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed