SCHEMBL4459649

SCHEMBL4459649

Clc1cc(Cl)c(-c2ccc(Cl)c(Cl)c2Cl)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.54
ALDH1A1 P00352 3/20 0.46
TP53 P04637 1/20 0.42
CYP3A4 P08684 3/20 0.39
MAPK1 P28482 1/20 0.39
TSHR P16473 3/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
RECQL P46063 1/20 0.36
PDK2 Q15119 1/20 0.34
ALPL P05186 2/20 0.34
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449569 0.83 AHR (0.58) AHRALDH1A1CYP3A4MAPK1TSHR
SCHEMBL4450365 0.81 AHR (0.56) AHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL5685708 0.80 AHR (0.60) AHRALDH1A1CYP3A4MAPK1TSHR
SCHEMBL4450510 0.80 AHR (0.48) AHRALDH1A1CYP3A4MAPK1TSHR
SCHEMBL29492227 0.79 AHR (0.52) AHRALDH1A1CYP3A4MAPK1TDP1
SCHEMBL2230317 0.79 AHR (0.52) AHRALDH1A1CYP3A4MAPK1TSHR
SCHEMBL30301086 0.79 AHR (0.52) AHRALDH1A1CYP3A4MAPK1TSHR
SCHEMBL4453307 0.79 AHR (0.52) AHRALDH1A1CYP3A4MAPK1TDP1
SCHEMBL8165912 0.78 ALDH1A1 (0.75) AHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL4456481 0.78 ALDH1A1 (0.43) AHRALDH1A1MAPK1TSHRPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed