Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224669 | 0.85 | MEN1 (0.46) | ALDH1A1MAOAMAOBTP53TDP1 | |
| SCHEMBL4452395 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRSLC6A4MAOAMAOB | |
| SCHEMBL19631194 | 0.80 | MAOA (0.53) | ALDH1A1TSHRSLC6A4MAOAMAOB | |
| SCHEMBL8151125 | 0.80 | TP53 (0.47) | ALDH1A1TSHRTP53TDP1FAAH | |
| SCHEMBL10339845 | 0.79 | NPC1 (0.46) | ALDH1A1TP53TDP1CYP2D6CYP1A2 | |
| SCHEMBL7171513 | 0.77 | TP53 (0.48) | ALDH1A1TSHRSLC6A4TP53TDP1 | |
| SCHEMBL10616284 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRMAOAMAOBTP53 | |
| SCHEMBL7180862 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRMAOAMAOBTP53 | |
| SCHEMBL9232510 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHRTP53TDP1FAAH | |
| SCHEMBL13653519 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TSHRSLC6A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211363-B1 | 3-PHENYLTHIOMETHYLSTYRENE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND ANTIALLERGIC AGENT AND TYROSINEKINASE INHIBITING AGENT CONTAINING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-01-02 | — | — | EP | claimed |
| US-4853403-A | 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-01 | — | — | US | claimed |
| EP-0211363-A2 | 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-02-25 | — | — | EP | claimed |
| JP-5032546-A | — | — | None | — | — | JP | disclosed |
| JP-5000938-A | — | — | None | — | — | JP | disclosed |
| JP-7233055-A | — | — | None | — | — | JP | disclosed |
| EP-1524289-B1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-20070149639-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | HORIKOSHI HIROSHI | 2007-06-28 | — | — | US | disclosed |
| EP-1524289-A1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| JP-H07233055-A | PROPHYLACTIC AND THERAPEUTIC AGENT FOR INTIMAL HYPERTROPHY OF ARTERY | KANEGAFUCHI CHEM IND CO LTD | 1995-09-05 | — | — | JP | disclosed |
| JP-H05938-A | PREVENTING OR TREATING AGENT FOR PNEUMONIA | KANEGAFUCHI CHEM IND CO LTD | 1993-01-08 | — | — | JP | disclosed |
| EP-0211363-B1 | 3-PHENYLTHIOMETHYLSTYRENE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND ANTIALLERGIC AGENT AND TYROSINEKINASE INHIBITING AGENT CONTAINING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-01-02 | — | — | EP | disclosed |
| EP-0211363-B1 | 3-PHENYLTHIOMETHYLSTYRENE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND ANTIALLERGIC AGENT AND TYROSINEKINASE INHIBITING AGENT CONTAINING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-4853403-A | 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-01 | — | — | US | disclosed |
| US-4853403-A | 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-01 | — | — | US | disclosed |
| US-4853403-A | 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0211363-A2 | 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-02-25 | — | — | EP | disclosed |
| EP-0211363-A2 | 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-02-25 | — | — | EP | disclosed |
| EP-0211363-A2 | 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiting agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-02-25 | — | — | EP | disclosed |