SCHEMBL4462226

SCHEMBL4462226

COCCOCCOc1cc2c(cc1O)C1(CC2(C)C)CC(C)(C)c2cc(OCCOCCOC)c(O)cc21

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.40
RARG P13631 9/20 0.33
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
OPRK1 P41145 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4455722 0.96 OPRM1 (0.42) OPRM1RARGRARARARB
SCHEMBL4467219 0.89 DRD1 (0.35) OPRM1
SCHEMBL4466037 0.89 OPRM1 (0.37) OPRM1
SCHEMBL4460159 0.88 RXRA (0.38) OPRM1RARARARBALDH1A1
SCHEMBL4459350 0.88 DRD1 (0.36) OPRM1
SCHEMBL12581594 0.85 KDM1A (0.35) OPRM1RARGRARARARBPOLB
SCHEMBL4471742 0.85 L3MBTL1 (0.39) ALDH1A1POLBRAB9A
SCHEMBL4469326 0.84 RXRA (0.38) OPRM1RARB
SCHEMBL4474023 0.83 RXRA (0.41) RARGRARARARB
SCHEMBL4464095 0.82 RXRA (0.33) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed