SCHEMBL4460372

SCHEMBL4460372

Cc1ccc(-c2cccc(C)c2-c2ccc(C)cc2)cc1.Cc1ccc(C(c2ccc(C)cc2C)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.36
ENPP1 P22413 1/20 0.34
PDK2 Q15119 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 2/20 0.33
ELANE P08246 1/20 0.33
CYP2A6 P11509 1/20 0.33
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
TSHR P16473 2/20 0.31
MAPK1 P28482 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3355657 0.83 ENPP1 (0.42) ADORA3ENPP1NPC1RAB9AMEN1
Methane SCHEMBL11860700 0.81 ENPP1 (0.41) ADORA3ENPP1NPC1RAB9AMEN1
SCHEMBL2235269 0.75 TDP1 (0.46) CYP1A2CYP2A6MAOAMAOBCASR
SCHEMBL10452707 0.75 PTGS2 (0.45) ENPP1NPC1RAB9AMEN1KMT2A
SCHEMBL261913 0.73 ENPP1 (0.37) ADORA3ENPP1NPC1RAB9AMEN1
SCHEMBL1044029 0.71 ACHE (0.44) ADORA3CYP1A2CYP2A6CA1CA2
SCHEMBL2163513 0.70 CYP3A4 (0.42) CA12CA1CA2CA9TP53
SCHEMBL1556559 0.69 MYC (0.48) NPC1RAB9ACYP2A6CA12CA1
SCHEMBL6564117 0.69 RAB9A (0.46) ENPP1NPC1RAB9AKMT2ATSHR
SCHEMBL8724561 0.69 ADORA3 (0.38) ADORA3ENPP1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498432-B1 PROCESS FOR PRODUCING HIGHLY FLOWABLE PROPYLENE POLYMER AND HIGHLY FLOWABLE PROPYLENE POLYMER IDEMITSU KOSAN CO (JP) 2009-09-02 EP disclosed
US-20050159566-A1 improved flexibility, and transparency, heat sealability and hot tackiness; good softness, a less stickiness, and an good compatibility with polyolefin resins; for sanitary materials, packing, bookbinding, fibers IDEMITSU KOSAN CO., LTD (JP) 2005-07-21 US disclosed
EP-1498432-A1 PROCESS FOR PRODUCING HIGHLY FLOWABLE PROPYLENE POLYMER AND HIGHLY FLOWABLE PROPYLENE POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 2005-01-19 EP disclosed