SCHEMBL4461196

SCHEMBL4461196

C[C@@H](N)C(=O)c1ccc(C=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
TYR P14679 1/20 0.47
PARP10 Q53GL7 1/20 0.46
PARP3 Q9Y6F1 1/20 0.46
ALDH1A3 P47895 2/20 0.42
CYP2A6 P11509 3/20 0.41
ALDH5A1 P51649 1/20 0.41
ABAT P80404 1/20 0.41
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP2A13 Q16696 1/20 0.38
EPHX2 P34913 1/20 0.37
NR1H4 Q96RI1 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP7 P09237 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20559900 0.85 ALDH1A1 (0.48) ALDH1A1TYRPARP10PARP3ALDH1A3
SCHEMBL7402179 0.83 ALDH1A1 (0.56) ALDH1A1TYRPARP10PARP3ALDH1A3
SCHEMBL8936829 0.80 ALDH1A1 (0.44) ALDH1A1TYRPARP10PARP3ALDH1A3
Alanine SCHEMBL17848057 0.79 ALDH1A1 (0.52) ALDH1A1TYRPARP10PARP3ALDH1A3
SCHEMBL9364482 0.77 LMNA (0.44) ALDH1A1PARP10ADRB2ADRB1ADRB3
SCHEMBL2631353 0.77 ALDH1A1 (0.52) ALDH1A1
SCHEMBL16694617 0.77 ALDH1A1 (0.52) ALDH1A1
SCHEMBL28228323 0.77 ALDH1A1 (0.52) ALDH1A1
Hydroxylated Completely Delakylated Diethylpropion SCHEMBL5319402 0.77 CA1 (0.50) TYRHSD17B10
SCHEMBL6982065 0.77 ALDH1A1 (0.58) ALDH1A1TYRPARP10PARP3ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7514243-B2 Process for producing dipeptides KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-04-07 US disclosed