Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 7/20 | 0.64 |
| ▸ | CASP7 | P55210 | 5/20 | 0.64 |
| ▸ | CASP1 | P29466 | 4/20 | 0.64 |
| ▸ | CASP9 | P55211 | 4/20 | 0.64 |
| ▸ | CTSK | P43235 | 5/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | CASP4 | P49662 | 2/20 | 0.51 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.51 |
| ▸ | CASP5 | P51878 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038936 | 0.96 | CASP3 (0.69) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL7168373 | 0.95 | CASP1 (0.58) | CASP3CASP7CASP1CASP9CTSK | |
| SCHEMBL15939366 | 0.92 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CTSK | |
| SCHEMBL29818103 | 0.92 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CTSK | |
| SCHEMBL2038060 | 0.89 | CASP3 (0.63) | CASP3CASP7CASP1CASP9CTSK | |
| SCHEMBL2039051 | 0.87 | CASP3 (0.69) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL4952116 | 0.87 | CASP3 (0.60) | CASP3CASP7CASP1CASP9CTSK | |
| SCHEMBL2043662 | 0.86 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL29362585 | 0.85 | CASP3 (0.76) | CASP3CASP7CASP1CASP9CTSK | |
| SCHEMBL2034855 | 0.84 | CAPN1 (0.48) | CASP3CASP7CASP1CASP9CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080808-A2 | PHARMACEUTICAL FOR THE TREATMENT OF FIBROSING PULMONARY DISEASES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2009-07-02 | — | — | WO | disclosed |