Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 13/20 | 0.60 |
| ▸ | CASP7 | P55210 | 8/20 | 0.55 |
| ▸ | CASP1 | P29466 | 5/20 | 0.55 |
| ▸ | CASP9 | P55211 | 5/20 | 0.55 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.52 |
| ▸ | CASP6 | P55212 | 2/20 | 0.52 |
| ▸ | CASP4 | P49662 | 3/20 | 0.52 |
| ▸ | CASP10 | Q92851 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CASP5 | P51878 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033191 | 0.96 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL713780 | 0.96 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL2043662 | 0.93 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL2038936 | 0.91 | CASP3 (0.69) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL29384302 | 0.89 | CASP3 (0.60) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL26071633 | 0.89 | CASP3 (0.60) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL4466395 | 0.89 | CASP3 (0.60) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL15939366 | 0.88 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL2038060 | 0.88 | CASP3 (0.63) | CASP3CASP7CASP1CASP9CASP8 | |
| SCHEMBL4461379 | 0.87 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311036-A1 | Imaging of Neural and Organ Injury or Damage | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-12-18 | — | — | US | claimed |
| WO-2006122237-A2 | IMAGING OF NEURAL AND ORGAN INJURY OR DAMAGE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2006-11-16 | — | — | WO | claimed |
| US-20080311036-A1 | Imaging of Neural and Organ Injury or Damage | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-12-18 | — | — | US | disclosed |
| WO-2006122237-A2 | IMAGING OF NEURAL AND ORGAN INJURY OR DAMAGE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2006-11-16 | — | — | WO | disclosed |