SCHEMBL15939366

SCHEMBL15939366

CC(C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)C(=O)CF

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 15/20 0.64
CASP7 P55210 11/20 0.64
CASP1 P29466 7/20 0.64
CASP9 P55211 5/20 0.64
CASP4 P49662 3/20 0.52
CASP10 Q92851 3/20 0.52
CASP8 Q14790 2/20 0.52
CASP5 P51878 1/20 0.52
CASP6 P55212 1/20 0.52
CTSB P07858 2/20 0.48
CTSK P43235 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2038936 0.96 CASP3 (0.69) CASP3CASP7CASP1CASP9CASP4
SCHEMBL2043662 0.93 CASP3 (0.56) CASP3CASP7CASP1CASP9CASP4
SCHEMBL4461379 0.92 CASP3 (0.64) CASP3CASP7CASP1CASP9CASP4
SCHEMBL2038060 0.91 CASP3 (0.63) CASP3CASP7CASP1CASP9CASP4
SCHEMBL2033191 0.90 CASP3 (0.56) CASP3CASP7CASP1CASP9CASP4
SCHEMBL713780 0.90 CASP3 (0.56) CASP3CASP7CASP1CASP9CASP4
SCHEMBL4952116 0.88 CASP3 (0.60) CASP3CASP7CASP1CASP9CASP4
SCHEMBL2039051 0.87 CASP3 (0.69) CASP3CASP7CASP1CASP9CASP4
SCHEMBL7168373 0.86 CASP1 (0.58) CASP3CASP7CASP1CASP9CTSB
SCHEMBL2040978 0.86 CASP3 (0.57) CASP3CASP7CASP1CASP9CASP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 US disclosed
US-20240287574-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2024-08-29 US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 US disclosed
US-20220017944-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2022-01-20 US disclosed
EP-3401406-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GmbH (DE) 2018-11-14 EP disclosed
EP-2976424-B1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2018-10-03 EP disclosed
EP-2761020-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2018-06-13 EP disclosed
US-20160348151-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2016-12-01 US disclosed
US-20160281132-A1 STABILIZATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2016-09-29 US disclosed
US-20160281133-A1 STABILIZATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2016-09-29 US disclosed
EP-2761000-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2016-03-16 EP disclosed
US-20150275268-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2015-10-01 US disclosed
US-20140227688-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2014-08-14 US disclosed
US-20140227687-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 CASP3 1797/4885CASP7 1282/4885CASP1 1854/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 CASP3 1797/4885CASP7 1282/4885CASP1 1854/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 CASP3 1797/4885CASP7 1282/4885CASP1 1854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.