SCHEMBL446138

SCHEMBL446138

[CH2]CCc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8672544 0.78 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3DAO
SCHEMBL10764275 0.77 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL146899 0.72
SCHEMBL13258720 0.72 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3DAO
SCHEMBL6130305 0.69 TAAR1 (0.30)
SCHEMBL24063638 0.69 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3DAO
SCHEMBL24384254 0.67 TSHR (0.30)
SCHEMBL172098 0.67 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3DAO
SCHEMBL7331916 0.67 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3DAO
SCHEMBL3113744 0.67 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230288383-A1 METHOD FOR ANALYZING COFFEE COMPONENT SHIMADZU CORPORATION (JP) 2023-09-14 US claimed
CN-115308347-B Analysis method of nitrogen oxide impurities in topiroxostat 江苏知原药业股份有限公司 2023-09-08 CN claimed
CN-115308347-A Analysis method of nitrogen oxide impurities in topirolast 江苏知原药业股份有限公司 2022-11-08 CN claimed
CN-114062530-A Determination and analysis method for isomer impurities in crude chlorpheniramine maleate product 浙江美诺华药物化学有限公司 2022-02-18 CN claimed
CN-108885195-B Method for analyzing copolymer of conjugated diene compound and aromatic vinyl compound 株式会社岛津制作所 2021-09-24 CN claimed
US-20210178289-A1 METHODS OF ASSAYING TROPOLONE LONZA LTD (CH) 2021-06-17 US claimed
EP-3704488-A1 METHODS OF ASSAYING TROPOLONE Lonza Ltd (CH) 2020-09-09 EP claimed
CN-111512161-A Method for analyzing tropolone 隆萨有限公司 2020-08-07 CN claimed
CN-110621711-A Photocurable composition containing fluorine-based polymer 捷恩智株式会社 2019-12-27 CN claimed
WO-2019113050-A1 METHODS OF ASSAYING TROPOLONE LONZA LTD (CH) 2019-06-13 WO claimed
EP-2096128-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION Chisso Corporation (JP) 2009-09-02 EP claimed
EP-1416064-B1 Method of coating micro-electromechanical devices EASTMAN KODAK CO (US) 2008-05-07 EP claimed
US-20070135602-A1 Fluorinated polymer and polymer composition CHISSO CORPORATION 2007-06-14 US claimed
US-7125949-B2 Fluorinated sol-gel electro-optic materials, process for producing same, and devices therefrom LUMERA CORPORATION (US) 2006-10-24 US claimed
WO-2005070547-A2 POLYMER SUSTAINED MICROELECTRODES, PROCESSES FOR FABRICATING SAME, PROCESSES FOR FABRICATING ELECTRO-OPTIC POLYMER DEVICES INCORPORATING SAME, AND FLUORINATED SOL-GEL ELECTRO-OPTIC MATERIALS LUMERA CORPORATION (US) 2005-08-04 WO claimed
US-20050159574-A1 Fluorinated sol-gel electro-optic materials, process for producing same, and devices therefrom LUMERA CORPORATION 2005-07-21 US claimed
US-6808745-B2 MIXING SILANE COUPLING AGENT WITH LOW VOLATILE MATRIX MATERIAL IN COATING CONTAINER, PLACING MICROELECTROMECHANICAL SYSTEMS DEVICE IN VACUUM DEPOSITION CHAMBER, PUMPING TO PREDETERMINED PRESSURE, CHEMICALLY VAPOR DEPOSITING SILANE ON SURFACE EASTMAN KODAK COMPANY 2004-10-26 US claimed
EP-1416064-A2 Method of coating micro-electromechanical devices EASTMAN KODAK COMPANY (US) 2004-05-06 EP claimed
US-20040037956-A1 Vapor deposition a silane coupling agent on electronics, under control pressure in vacuum chamber; preventing non-uniform coatings EASTMAN KODAK COMPANY 2004-02-26 US claimed
US-5492792-A OPTICAL CARD OR DISKS; EXCELLENT LIGHT SENSITIVITY WITHIN NEAR INFRARED REGION AND HEAT RESISTANCE; STORE INFORMATIONSAT HIGH DENSITY CANON KABUSHIKI KAISHA (JP) 1996-02-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210178289-A1 METHODS OF ASSAYING TROPOLONE TTPA, SHBG, TPM4 SLC6A2 3547/4885SLC6A4 2682/4885SLC6A3 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.