Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462380 | 0.81 | ALDH1A1 (0.50) | KCNH2PDK2HSP90AA1HSP90AB1GAA | |
| SCHEMBL5634575 | 0.80 | KCNH2 (0.54) | KCNH2HSP90AA1HSP90AB1GAA | |
| SCHEMBL4599280 | 0.78 | KCNH2 (0.47) | KCNH2PDK2HSP90AA1HSP90AB1GAA | |
| SCHEMBL19226402 | 0.76 | MEN1 (0.63) | PDK2KDM1A | |
| SCHEMBL26424704 | 0.76 | MEN1 (0.63) | PDK2KDM1A | |
| SCHEMBL14019253 | 0.76 | GAA (0.65) | GAA | |
| SCHEMBL8605250 | 0.74 | PKM (0.61) | KCNH2HSP90AA1HSP90AB1GAA | |
| SCHEMBL2132882 | 0.72 | EPHX1 (0.63) | PDK2KDM1AHRH4 | |
| SCHEMBL7881494 | 0.72 | EPHX1 (0.63) | PDK2KDM1AHRH4 | |
| SCHEMBL2132888 | 0.72 | EPHX1 (0.63) | PDK2KDM1AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507760-B2 | N-type calcium channel blockers | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-03-24 | — | — | US | claimed |