SCHEMBL4462933

SCHEMBL4462933

CC(CCC1C=Cc2ccccc21)[Zr](Cl)(Cl)([SiH2]Cc1ccccc1)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.35
HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4463649 0.88 SIGMAR1 (0.34) SIGMAR1HTR6
SCHEMBL4479925 0.87 SIGMAR1 (0.33) SIGMAR1HTR6
SCHEMBL6061566 0.78 HTR6 (0.35) SIGMAR1HTR6
SCHEMBL6061490 0.77 HTR6 (0.35) SIGMAR1HTR6
SCHEMBL4479627 0.76 HTR6 (0.42) SIGMAR1HTR6
SCHEMBL6062623 0.75 HTR6 (0.38) SIGMAR1HTR6
SCHEMBL3820447 0.74 SIGMAR1 (0.35) SIGMAR1HTR6
SCHEMBL6062003 0.74 HTR6 (0.38) SIGMAR1HTR6
Hydrochloric Acid SCHEMBL6061569 0.73 HTR6 (0.36) SIGMAR1HTR6
SCHEMBL4471513 0.72 HTR6 (0.35) SIGMAR1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142147-A1 Catalysts compositions for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA, S.A. (ES) 2006-06-29 US claimed
EP-1671983-A1 Catalysts compositions for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA S.A. (ES) 2006-06-21 EP claimed
EP-1671983-B1 Catalysts compositions for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA SA (ES) 2009-02-25 EP disclosed
US-20060142147-A1 Catalysts compositions for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA, S.A. (ES) 2006-06-29 US disclosed
EP-1671983-A1 Catalysts compositions for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA S.A. (ES) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142147-A1 Catalysts compositions for the polymerization and copolymerization of alpha-olefins B2M, OPRM1, POLM SIGMAR1 704/4885HTR6 1387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.