SCHEMBL3820447

SCHEMBL3820447

Cl[Zr](Cl)([SiH2]Cc1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.35
HTR6 P50406 1/20 0.35
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4479627 0.81 HTR6 (0.42) SIGMAR1HTR6
SCHEMBL7641474 0.76 HTR6 (0.33) SIGMAR1HTR6HTR2A
SCHEMBL4462933 0.74 SIGMAR1 (0.35) SIGMAR1HTR6
SCHEMBL4463649 0.74 SIGMAR1 (0.34) SIGMAR1HTR6
SCHEMBL7208819 0.73 HTR6 (0.38) SIGMAR1HTR6HTR2A
SCHEMBL4445238 0.73 SIGMAR1 (0.35) SIGMAR1HTR6HTR2A
SCHEMBL4846527 0.72 HTR6 (0.33) HTR6HTR2A
SCHEMBL3304642 0.72
SCHEMBL7883110 0.71 SIGMAR1 (0.36) SIGMAR1HTR6HTR2A
SCHEMBL7772297 0.71 SIGMAR1 (0.36) SIGMAR1HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1597632-B1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2013-03-27 EP claimed
EP-1597632-A4 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2009-08-26 EP claimed
US-7378206-B2 Non-magnetic monocomponent positive toner composition having superior transfer efficiency LG CHEM, LTD. (KR) 2008-05-27 US claimed
US-20060105260-A1 Non-magnetic monocomponent positive toner composition having superior transfer efficiency LG CHEM, LTD. (KR) 2006-05-18 US claimed
EP-1597632-A1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG Chem, Ltd. (KR) 2005-11-23 EP claimed
WO-2004079456-A1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEM, LTD. (KR) 2004-09-16 WO claimed
US-6641925-B1 Metallocene system catalyzed cycloolefin copolymer laminated to polyvinyl chloride; extrusion coated film as packaging TICONA GMBH (DE) 2003-11-04 US claimed
EP-0791611-B1 Process for the preparation of cycloolefin polymers TICONA GMBH (DE) 2003-02-12 EP claimed
EP-1597632-B1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2013-03-27 EP disclosed
US-8329841-B2 Photoreactive polymer and method for preparing the same LG CHEM, LTD. (KR) 2012-12-11 US disclosed
US-20120149848-A1 PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2012-06-14 US disclosed
EP-1597632-A4 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2009-08-26 EP disclosed
US-7378206-B2 Non-magnetic monocomponent positive toner composition having superior transfer efficiency LG CHEM, LTD. (KR) 2008-05-27 US disclosed
US-20060105260-A1 Non-magnetic monocomponent positive toner composition having superior transfer efficiency LG CHEM, LTD. (KR) 2006-05-18 US disclosed
US-5646220-A I.E. NORBORNENE-ETHYLENE COPOLYMERS; PHASE PROMOTERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-08 US disclosed
US-5610253-A Cycloolefin polymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-03-11 US disclosed
US-5475060-A Phase promoters HOECHST AG (DE) 1995-12-12 US disclosed
US-5422409-A Stopping polymerization when molecular weight distribution Mw/Mn is less than 2 HOECHST AKTIENGESELLSCHAFT 1995-06-06 US disclosed
US-5331057-A Cycloolefin block copolymers and a process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-19 US disclosed
US-5087677-A Catalyst of a metallocene and an aluminoxane HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149848-A1 PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME PCNA, LCP1, CCND2 SIGMAR1 4485/4885HTR6 3377/4885HTR2A 3002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.